Cyp2c9 - Study guides, Class notes & Summaries

What are the 6 general principles of psychopharmacological treatment? Safety Tolerability Efficacy Practicality Treatment accessibility Treatment compliance Pharmacokinetics How the drug moves in the body. (ex. Where is it absorbed? How and where is it metabolized? Where is it excreted?) Pharmacodynamics What the drug does to the body. (consider mechanism of action) Define First-generation antipsychotics Referred to as Typical Antipsychotics. Most have strong bond w...

Midterm Exam: NR566/ NR 566 Advanced Pharmacology for Care of the Family Complete Guide – (Weeks 1-4) - (Latest Update 2024/ 2025) - Questions and Verified Answers| 100% Correct |Grade A – Chamberlain Q: Review of CYP450 Answer: • Amiodarone as CYP450 Inhibitor o Amiodarone inhibits CYP450 enzymes, affecting the metabolism of medications like Warfarin. o Inhibition of CYP2C9 by Amiodarone can lead to increased blood levels of Warfarin. • Effects of Inducers and Inhibitors on Me...

Warfarin (Coumadin) - ️️CYP2C9 and VKORC1 - Vitamin K antagonist; metabolized primarily via oxidation in the liver by CYP2C9 and exerts its anticoagulant effect by inhibiting the protein vitamin epoxide reductase complex, subunit 1 (VKORC1) Chronic Myelogenous Leukemia (CML) - ️️t(9;22) aka Philadelphia Chromosome, translocation occurs within two genes: the breakpoint cluster region (BCR) on chr.22 and the cellular counter part of the Abelson Leukemia virus tyrosine kinase (c-abl) o...

Advanced Pharmacology Mock Rehearsal Exam| 2025/2026 Certification| Verified Q&A 1. What term describes the fraction of an administered drug that reaches the systemic circulation? Bioavailability 2. Which pharmacokinetic phase involves the movement of drugs from the bloodstream to the tissues? Distribution 3. In pharmacodynamics, what term describes the maximum effect a drug can produce, regardless of dose? Efficacy 4. Which process describes the body's ability to change dru...

PHARMACOLOGY - PANCE REVIEW WITH COMPLETE SOLUTIONS 100% IRreversible platelet effect - correct answer Aspirin (acetylsalicylic acid = ASA Kids with viral infection - give aspirin ---> will cause - correct answer Reye's syndrome *ASA Triad (asthma, nasal polyps) caution will cause _____ in ___ patients - correct answer bronchospam in asthma patients medication that Antagonizes vitamin K - correct answer Warfarin reverse warfarin in • Non-Life-Threatening Hemorrhage - corr...

NR 565 PHARM MIDTERM EXAM REVIEW QUESTIONS AND ANSWERS, GRADED A+/ VERIFIED/ CYP2D6 - -Need to increase doses of SSRI, beta blockers etc. Codeine can be deadly CYP2C9 - -Decrease warfarin dose Test for gene VCORC1 mutation CYP3A4 - -Decreases elimination Increase toxicity of Amio Schedule I - -no accepted medical use in the US it may not be prescribed. heroin,various opium derivatives,hallucinogenic substances Schedule II - -No refills, no telephone orders Narcotics, Stimulants, Depr...

BCR;ABL1 fusion protein → t(9;22)(q34;q11) Acute Promyelocytic Leukemia (APL) → t(15;17) a fusion of PML and RARA Burkitt's Lymphoma → t(8;14) the breakpoints on chr.8 are spread of 190 kbp region 5' to and within the CMY C gene Follicular Cell Lymphoma (FCL) → t(14;18) translocation disregulate BCL2, which inhibits apoptosis in B lymphocytes, which leads to survival of genetically damaged cells Mantle Cell (MCL) → t(11;14) translocation increases expression of CCND1 ...

Currently, all CCBs on the market target the __-type voltage activated calcium channel. A) T B) N C) R D) L E) P/QD) L *Currently, all CCBs on the market traget the L-type channel.* CCBs have greater effect on *arterial* or *venous smooth muscle.*CCBs have greater effect on *arterial smooth muscle.* "All CCBs relax arterial smooth muscle, but they have less effects on venous beds." True or false... CCBs have no significant effect on cardiac preload.True! "CCBs inhibit ca...

CASE STUDY QUESTIONS: GENETIC CODE EXAM QUESTIONS WITH VERIFIED SOLUTIONS GRADED A++ Why would someone with this type of mutation be at a much higher risk for overdosing on a prescribed drug? When a drug is prescribed, it is prescribed at a dose that assumes that the person's body would be metabolizing (breaking down) the drug at a specific rate. If the person lacks the enzymes (or enzyme functions) that are responsible for this metabolism, a "normal" dose can become an "overdose...

What law stated that there were no need for clinical trials and generic alternatives for drugs with expired patents could be used? Waxman Law What is St. Johns Wort used for in Germany and the US? Germany-treats depression, anxiety, and insomnia US- dietary supplement to promote emotional balance What is Hypericins half life? 25 hours When do you reach peak blood levels taking hypericin? 5 hrs What does quercitin inhibit? What about hyperforin? CYP1A2 CYP2D6 and CYP2C9 What does hypericum a...