Comprehensive Pharmacology Q&A Bundle

Calcium channel blockers (CCBs) lower BP by __________ Vasodilation CCBs differ from nitrates in that they do not cause vasodilation of ___________ Veins (venous system) Dihydropyridine CCBs primarily affect _________ Arterioles The three effects of the CCBs verapamil and diltiazem on the heart a...

Calcium Channel Blockers -CCBs are like "valium" for your heart --Valium calms you down. Therefore, CCB relaxes and slows down the heart ---If the heart is tachycardic, tachyarrhythmia, or heart attack → needs to be rested → GIVE CCB ---If you are in shock, or you are in heart block → needs to...

Calcium Channel Blockers Hypertension Angina Pectoris Cardiac dysrhythmias CCBs that target both vascular smooth muscle and the hearts NONdihyrdopyridines Verapamil Diltiazem CCB that targets vascular smooth muscle only DIHYDROPYRIDINES Nifedipine Calcium channel open Contractile process Calcium...

All CCB are racemic mixtures except? Dilt and Nifedipine Non-Dihydropyridines Verapamil and diltiazem Dihydropyridines Nifedipine, Nicardipine, Nimodipine, Felodipine, Isradipine, Nisoldipine Amlodipine, Clevidipine Adverse affects of CCBs are similar except that dihydropyridines never cause what...

nondihydropyridine CCB include verapamil & diltiazem Verapamil is a NDH CCB Diltiazem is a NDH CCB Nondihydropyridine CCBs can be used to treat - HTN - stable angina - arrhythmias - atrial fibrillation NDH CCB deacrease HR & slow AV node conduction * may cause bradycardia & AV block * Counselin...

A diabetic patient suffers from effort angina, they have tried beta blockers before but are worried about experiencing a hypoglycemic incident while on the beta blocker. What would be the next best drug to treat this patient's angina? a. Verapamil b. Nifedipine c. Metoprolol d. Bumetanide ANS: A - v...

Ca2+ Channel Blockers (CCBs) groups Dihydropyridine (DHP) groups NonDihydropyridine groups Dihydropyridine (DHP) groups *Amlodipine (Norvasc®) Felodipine Isradipine Nicardipine Nifedipine (Procardia®) Nimodipine Nisoldipine NonDihydropyridine groups *Verapamil (Calan®) Diltiazem (Cardizem®) ...

What are the three main classes of calcium channel blocking drugs? 1. Dihydropyridine 2. Benzothiazepines 3. Phenylalkylamines What drug is the benzothiazepine prototype? Diltiazem What drug is the phenylakylamine prototype? Verapamil What is the common suffix used by the dihydropyridine class? -...

What is the ion that is important for the depolarization of the nodal cell? Ca++ What are the potential effects of CCBs? 1) Reduce cardiac Automaticity 2) Reduce AV nodal conduction 3) Cause vasodilation What are the three main chemical classes of CCBs? 1) Phenylalkylamines 2) Benzothiazepines 3) ...

Currently, all CCBs on the market target the __-type voltage activated calcium channel. A) T B) N C) R D) L E) P/QD) L *Currently, all CCBs on the market traget the L-type channel.* CCBs have greater effect on *arterial* or *venous smooth muscle.*CCBs have greater effect on *arterial sm...

calcium channel blockers Effect the heart, and blood vessels. CCBs are widely used to treat hypertension, angina pectoris and cardias dysrhythmias. calcium and the heart Calcium regulates contraction in vascular smooth muscle and cardiac muscle. In cardiac/vascular smooth muscle (VSM), the influx...

Calcium Channel Blockers (CCBs) CCBs work by decreasing calcium entry through calcium channels. By regulating the movement of calcium, contraction of vascular smooth muscle is controlled, which causes blood vessels to dilate. This reduces blood pressure and workload on the heart, so this type of med...

The primary cause of angina pectoris is an imbalance between --- --- of the heart and --- --- to the heartoxygen requirement; oxygen supply episodes of angina in unstable angina occur at --rest unstable angina is typically caused by -- -- around an atherosclerotic plaque causing a reduction in blo...

Main effects of CCBs (3) Slow HR Decrease BP SM relaxation 3 classes of dihydropyridines CCBs End in -Dipine 1st gen (NNN) 2nd gen (FINc) 3rd gen (amlodipine) 3 classes of non-selective CCBs (Non-dihydropyridines) Phenylalkylamines Benzothiazepines Phenylbenzylamine Indications of CCBs (4)...