Regioselectivity - Study guides, Class notes & Summaries

Reagent = Nucleophile Only - ANSWER1° = Sn2 2° = Sn2 3° = Sn1 + E1 (polar medium necessary) Reagent = Strong Nucleophile & Strong Base - ANSWER1° = Sn2 2° = E2 3° = E2 Reagent = Weak Nucleophile and Weak Base - ANSWER1°/2° = No Reaction 3°/resonance stabilized carbocation = Sn1 + E1 (polar medium necessry Reagent = Base Only - ANSWER1° = E2 or Sn2 (if unhindered and no beta-hydrogen with unhindered base) 2° = E2 3° = E2 Examples of Only Nucleophiles - ANSWERCl⁻, ...

CHEM 210 Reactions Test Questions and Answers All Correct Describe the mechanism for the electrophilic addition of a strong acid. - Answer-Step 1) An alkene grabs a hydrogen off of a strong acid, forming a carbocation intermediate. Step 2) The conjugate base of the acid (an anion now) bonds to the open shell carbocation What is the regioselectivity of electrophilic addition reactions? - Answer-Markovnikov What is Markovnikov regioselectivity? - Answer-States that the major product is det...

electrophiles - ANSWERelectron seeking reagents that have room to accept a electron pair nucleophiles - ANSWERreagents seeking a nucleus to which to donate a pair of electrons proton transfer or protonation reaction - ANSWERthe transfer of a proton from one base to another transition state - ANSWERlying between the products and reactants free energy of activation (delta G double dagger) - ANSWERthe height of the barrier, the energy that the reactants attain in reaching the the transi...

Basicity rules - -strong base: unstable/reactive (ED groups) -weak base: stable (EW groups/more EN/bigger) Chair conformation - -more stable equitorial (slanted) -pointing up/pointing down=cis if both up -elimination: trans and diaxial Newman projection - -gauche: substituent groups adjacent to eachother -grab middle and turn to put in plane Enantiomers - -not superimposable mirror images -same besides stereochemistry Diastereomers - -mirror images but one stereocenter stays and...

Chem 210 – Reactions Questions 100% Answered!! Reagent = Nucleophile Only - ANSWER1° = Sn2 2° = Sn2 3° = Sn1 + E1 (polar medium necessary) Reagent = Strong Nucleophile & Strong Base - ANSWER1° = Sn2 2° = E2 3° = E2 Reagent = Weak Nucleophile and Weak Base - ANSWER1°/2° = No Reaction 3°/resonance stabilized carbocation = Sn1 + E1 (polar medium necessry Reagent = Base Only - ANSWER1° = E2 or Sn2 (if unhindered and no beta-hydrogen with unhindered base) 2° = E2 3° = E...

Chem 210 Exam II Questions & Answers 10electrophiles - ANSWERelectron seeking reagents that have room to accept a electron pair nucleophiles - ANSWERreagents seeking a nucleus to which to donate a pair of electrons proton transfer or protonation reaction - ANSWERthe transfer of a proton from one base to another transition state - ANSWERlying between the products and reactants free energy of activation (delta G double dagger) - ANSWERthe height of the barrier, the energy that the reac...

Reagent = Nucleophile Only - ANSWER1° = Sn2 2° = Sn2 3° = Sn1 + E1 (polar medium necessary) Reagent = Strong Nucleophile & Strong Base - ANSWER1° = Sn2 2° = E2 3° = E2 Reagent = Weak Nucleophile and Weak Base - ANSWER1°/2° = No Reaction 3°/resonance stabilized carbocation = Sn1 + E1 (polar medium necessry Reagent = Base Only - ANSWER1° = E2 or Sn2 (if unhindered and no beta-hydrogen with unhindered base) 2° = E2 3° = E2 Examples of Only Nucleophiles - ANSWERCl⁻, ...

electrophiles - ANSWERelectron seeking reagents that have room to accept a electron pair nucleophiles - ANSWERreagents seeking a nucleus to which to donate a pair of electrons proton transfer or protonation reaction - ANSWERthe transfer of a proton from one base to another transition state - ANSWERlying between the products and reactants free energy of activation (delta G double dagger) - ANSWERthe height of the barrier, the energy that the reactants attain in reaching the the transi...

What is the degree of substitution? <<ANSWERS>>>The number of alkyl groups a specific carbon is bonded to (more alkyl groups means more stable) What reagents are required in a dissolving metal reduction? <<ANSWERS>>>Na or Li, ammonia (NH3) as solvent Provide a summary of dissolving metal reduction <<ANSWERS>>>2 hydrogens (one equivalent) are added to an alkyne to form the E alkene (anti addition) What is the stereochemistry of the dissolving ...

electrophiles electron seeking reagents that have room to accept a electron pair nucleophiles reagents seeking a nucleus to which to donate a pair of electrons proton transfer or protonation reaction the transfer of a proton from one base to another transition state lying between the products and reactants free energy of activation (delta G double dagger) the height of the barrier, the energy that the reactants attain in reaching the the transition state e...