Mdsc 321 - Study guides, Class notes & Summaries

What is MHC? - answer-Major histocompatibility complex What was MHC first recognized for? - answer-Self/non-self discrimination in transplant rejection What is MHC absolutely essential for? - answer-Displaying an antigen to T-cells What is the only way T-cells can see antigens? - answer-In the context of self MHC How many classes of MHC are there? Define them and their function. - answer-I - presentations of antigens inside the cell to killer T-cells II - presentation of extracellul...

Types of Antigens - - Infection(bad foreign) - gut flora(good foreign) - cancer(bad self) - autoimmunity(good self) what's recognizes antigens? - - adaptive immune system - innate only can recongize PAMPS what are antigens? - - molecule that can interact(specifically) w immunoglobulin(Ig) receptor of B cells(or T cell receptor complexed w MHC) - cells see it immunogen - - molecule that induces specific immune response - all immunogens are antigens - not all antigens are immun...

What makes a good vaccine? - answer-Variolation or Inoculation (Safety) Vaccination (Cost) Effectiveness Type of Immunity Vaccine Production - answer-Dried up small pox scabs, ship live cows to make the vaccine, own farms for vaccine production, infect egg with virus to make the vaccine, DNA vaccines take a gene that codes for one of the proteins to inject with the piece of DNA. Can't control where gene goes. Vaccine Composition (Live Attenuated) - answer-Weakened or less virulent p...

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MDSC 321 Exam Study Guide Solutions immunology *functional definition* - ANSWERhow many organism interacts with the biological world. every living thing has a form of immunity. immuno provides a set of skills to allow you to question and understand these interactions; formulate answers based on evidence immunology *dictionary definition* - ANSWERfrom Latin "Immunis" meaning exemption from service/duty, and later exemption from disease. MODERN DEFINITION: Science of how our body recog...