Gms 6540 - Study guides, Class notes & Summaries
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GMS 6540 exam with complete answers
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Ras signaling 
- GTPase 
- promotes growth and proliferation 
- mutated in 20-30% of all cancers 
- point mutations are most common 
 
 
 
G12V mutation 
- blocks GAP binding 
- locks RAS in active state, promoting proliferation 
 
 
 
Q61K mutation 
- raises activation energy of GTP hydrolysis 
- blocking hydrolysis, keeping RAS active 
 
 
 
Hallmarks of cancer 
1) self-sufficiency in growth signals 
2) insensitivity to anti-growth signals 
3) unstable DNA 
4) metastasis 
5) evasion of apoptos...
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GMS 6540 ( Med Pharm IV): PROBLEM SET 1, GMS 6540 (Med Pharm IV): PROBLEM SET 2, GMS 6540 (Med Pharm IV): PROBLEM SET 3, GMS 6540 (Med Pharm IV): PROBLEM SET 4, GMS 6540 (Med Pharm IV): PROBLEM SET 5, GMS 6540 (Med Pharm IV): PROBLEM SET 6, GMS 6540 - Uni
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GMS 6540 ( Med Pharm IV): PROBLEM SET 1, GMS 6540 
(Med Pharm IV): PROBLEM SET 2, GMS 6540 (Med 
Pharm IV): PROBLEM SET 3, GMS 6540 (Med Pharm IV): 
PROBLEM SET 4, GMS 6540 (Med Pharm IV): 
PROBLEM SET 5, GMS 6540 (Med Pharm IV): 
PROBLEM SET 6, GMS 6540 -University of Florida
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GMS 6540 Exam Questions With Complete Solutions
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GMS 6540 Exam Questions With Complete Solutions
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GMS 6540 Homework Questions With Complete Solutions
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GMS 6540 Homework Questions With Complete Solutions
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GMS 6540 ( Med Pharm IV): PROBLEM SET 1 Cancer Biology Questions With Complete Solutions
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GMS 6540 ( Med Pharm IV): PROBLEM SET 1 Cancer 
Biology Questions With Complete Solutions
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GMS 6540 EXAM 2 QUESTIONS WITH ANSWERS
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GMS 6540 EXAM 2 QUESTIONS WITH ANSWERS
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