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GMS 6540 ( Med Pharm IV): PROBLEM SET 1 Cancer Biology Questions With Complete Solutions
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GMS 6540 ( Med Pharm IV): PROBLEM SET 1 Cancer Biology Questions With Complete Solutions
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GMS 6540 ( Med Pharm IV): PROBLEM SET 1 CancerBiology Questions With Complete Solutions
Genetic changes are required for which of the following to
occur? Select all that apply.
Initiation/Transformation of a cell
Formation of a pre-neoplastic lesion from an initiated cell
Formation of a malignant tumor from a pre-neoplastic lesion
Formation of clinical cancer from a malignant tumor
Metastasis of a clinical cancer Correct Answers
......
Initiation/Transformation of a cell
......
Formation of a malignant tumor from a pre-neoplastic lesion
Formation of clinical cancer from a malignant tumor
Metastasis of a clinical cancer
What effect would a G12V mutation in Ras have on ERK?
It would lead to increased activation of ERK.
It would lead to decreased activation of ERK.
It would increase the stability of ERK.
It would decrease the stability of ERK. Correct Answers It would
...... ......
lead to increased activation of ERK.
Are cancers more likely to develop mutation that activate or
inactivate Rb?
Activate
, Inactivate Correct Answers Inactivate
...... ......
Metabolites of nicotine commonly result in DNA point
mutations. Which type of DNA instability is this an example of?
Genetic instability
Chromosomal instability Correct Answers Genetic instability
...... .... ..
If a human cell underwent endoreduplication followed by failed
cytokinesis, how many chromosomes would you expect that cell
to now contain?
23
46
92
184
368 Correct Answers 184
...... ......
Which of the following statements is true regarding apoptosis.
It does not occur in our bodies under normal circumstances.
Is it a process to ensure cancer cell survival.
Cancer cells must avoid it.
Tumors seek to upregulate it.
It can only be triggered by factors outside the cell. Correct ......
Answers Cancer cells must avoid it.
.... ..
Which statement best describes the Warburg effect?
The switching of cancer cells from oxidative phosphorylation to
aerobic glycolysis
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