Caspases - Study guides, Class notes & Summaries

NBME PATHOLOGY EXAM WITH LATEST VERIFIED QUESTIONS AND 100% CORRECT ANSWERS GRADED A+ Apoptosis: - ANS-Programmed cell death. REQUIRES ATP. Can occur via the intrinsic or extrinsic pathways, both of which involve activation of cytosolic caspases which mediate cellular breakdown. ***Unlike necrosis, apoptosis does not involve significant inflammation. Involves eosinophilic cytoplasm, cell shrinkage, pyknosis and basophilia, membrane blebbing and karyorrhexis, and formation of apoptot...

Test Bank for Huether and McCance's Understanding Pathophysiology, Canadian Edition, 2nd Edition by Kelly Power, Stephanie Zettel, , Mohamed Toufic El-Hussein Table of Contents PART ONE: BASIC CONCEPTS OF PATHOPHYSIOLOGY Unit 1: The Cell 1. Cellular Biology 2. Genes and Genetic Diseases 3. Epigenetics and Disease 4. Altered Cellular and Tissue Biology 5. Fluids and Electrolytes, Acids and Bases Unit 2: Mechanisms of Self-Defense 6. Innate Immunity: Inflammation and Wound Healing 7...

NBME Pathology verified 100% full solution Apoptosis: - ANSWER-Programmed cell death. REQUIRES ATP. Can occur via the intrinsic or extrinsic pathways, both of which involve activation of cytosolic caspases which mediate cellular breakdown. ***Unlike necrosis, apoptosis does not involve significant inflammation. Involves eosinophilic cytoplasm, cell shrinkage, pyknosis and basophilia, membrane blebbing and karyorrhexis, and formation of apoptotic bodies which are phagocytosed. **DNA ladderin...

NSG5003 FINAL WEEK 10 QUIZ-QUESTIONS AND CORRECT ANSWERS Understanding the various steps of proteolytic cascades, such as caspase-mediated apoptosis and complement cascades, may be useful in designing drug therapy for which human diseases NSG5003 FINAL WEEK 10 QUIZ-QUESTIONS AND CORRECT ANSWERS Understanding the various steps of proteolytic cascades, such as caspase-mediated apoptosis and complement cascades, may be useful in designing drug therapy for which human diseases NSG5003 FINAL WEEK...

CBNS 150 FINAL TEST QUESTIONS & ANSWERS 2024/2025 What are the major players of apoptosis? - ANSWERS- Bax - Bcl2 - caspases - cytochrome c - APAF1 - Mitochondria Who is considered "guardian of the genome"? - ANSWERSp53 Why does p53+/+ cells have a lower percent survival after x-irradiation than p53-/- cells? - ANSWERSApoptosis is induced by WT p53 in response to DNA damage How many different types of cancer are there? - ANSWERSAbout as many as there are different types of c...

Bcl-2 ____ cell death - inhibits Bad, Bax and Bid _______ cell death - promote pro-apoptotic complexes insert into - outer mitochondrial membrane cytochrome c is usually in - the inner membrane space cytochrome c - moves electrons in electron transport chain cytochrome c binds ______ and _________ to form the ____________ - adaptor, caspases, apoptosome caspases - special kinds of proteases involved in cell death

19S - regulatory particle of proteasome 2 Categories of Epigenetics - DNA methylatioin and histone modification 20S - core particle of proteasome 26S proteasome - inhibited in sporadic parkinsonism 3 groups of Bcl-2 family proteins - 1. Group I - Anti-apoptitic 2. Group II - Inducers 3. Group III - Potentiate 3 key molecules of apoptosis - 1. Bcl-2 family proteins 2. Apaf-1 3. caspases 3 metabolic pathways that regulate aging - 1. Dietary restrictions 2. Insulin/Insulin-like Growth Fa...

MMSC490 Final Exam Questions with 100% Answers Humans possess about .............. different cell types. 100 200 500 1,000 - Answer️️ -200 In adult organisms, cell death must be balanced by cell growth. differentiation. renewal. migration. - Answer️️ -renewal The distinct series of changes that characterizes programmed cell death is called necrosis. apoptosis. sepsis. execution. - Answer️️ -apoptosis Cells that die as the result of acute injury undergo lysis. sepsis...

Insulin increases glucose transport into skeletal muscle cells by: - Increasing translocation of GLUT- 4-containing vesicles to the plasma membrane An inhibitor of the serine kinase GSK-3beta will have all of the following effects on insulin-resistant skeletal muscle except: - Cause decreased serine phosphorylation of IRS-1 in the presence of insulin. - Cause increased insulin-stimulated glucose transport. - Cause decreased insulin-stimulated tyrosine phosphorylation. - Cause reduced seri...

MMSC 490 Final Exam Questions with Correct Answers Humans possess about .............. different cell types. 100 200 500 1,000 - Answer-200 In adult organisms, cell death must be balanced by cell growth. differentiation. renewal. migration. - Answer-renewal The distinct series of changes that characterizes programmed cell death is called necrosis. apoptosis. sepsis. execution. - Answer-apoptosis Cells that die as the result of acute injury undergo lysis. sepsis. apoptosis. ...

Dysplasia - correct answer 1) Abnormal tissue growth 2) cells vary in size, shape & appearance Dysplasia ex - correct answer abnormal cells present in PAP smear of cervix (considered precancerous condition) Hyperplasia - correct answer 1) increase in number of cells of an organ/tissue (seen in epithelial & connective tissue only 2) muscle & nervous ...

MMSC490 Final Exam Questions with 100% Answers Humans possess about .............. different cell types. 100 200 500 1,000 - Answer️️ -200 In adult organisms, cell death must be balanced by cell growth. differentiation. renewal. migration. - Answer️️ -renewal The distinct series of changes that characterizes programmed cell death is called necrosis. apoptosis. sepsis. execution. - Answer️️ -apoptosis Cells that die as the result of acute injury undergo lysis. sepsis...