Translocations - Study guides, Class notes & Summaries

CMMB413 Midterm I Question and answers verified to passCMMB413 Midterm I Segmental aneusomy/contiguous gene syndromes - correct answer microdeletions - small deletions that delete a series of genes in a row Ex: DiGeorge syndrome 3 Mb deletion in 22q11.2 region more susceptible due to areas of repetition Clinical cytogenetics - correct answer practice of medical genetics by studying the structure and number of chromosomes and ID possible disorders/abnormalities Indications of chr...

What happens to a chromosome fragment in meiosis that does not have a centromere (aka, acentric fragment)? Ans: It is lost.... Is the outcome the different for the acentric fragment in mitosis? Ans: no What is the consequence of a terminal deletion in meiosis? Ans: gametes are absorbed What are 2 possible outcomes of 2 chromosome breaks occurring on the same chromosome arm? (note that one outcome has 2 parts to it) Ans: paracentric inversion is one and a acentric fragment with a chrom...

ADVANCED PATHOPHYSIOLOGY FINAL EXAM WITH COMPLETE SOLUTIONS What is the most common cause of Down syndrome? a. Paternal nondisjunction b. Maternal translocations c. Maternal nondisjunction d. Paternal translocation - C What does activation of the classical pathway begin with? a. Viruses b. Antigen-antibody complexes c. Mast cells d. Macrophages - B. Activation of the classical pathway begins only with the activation of protein C1 and is preceded by the formation of a complex ...

An ordered photographic display of a set of chromosomes from a single cell is a(n): A) metaphase spread. B) autosomal spread. C) karyotype. D) anaphase spread. - correct answer c An error in which homologous chromosomes fail to separate during meiosis is termed: A) aneuploidy. B) nondisjunction. C) polyploidy. D) anaplasia. - correct answer b A somatic cell that does not contain a multiple...

Two types of dispersal - Answer-active and passive What are the three ways species know how/when to disperse? - Answer-innate, learned or environmental cue response physical barriers - Answer-ocean, mountain Behavioural barriers - Answer-competition, zonation Anthropogenic barriers - Answer-human caused - roads, dams, poaching What is the most prominent thing preventing dispersal - Answer-Barriers range expansion - Answer-the idea that the geographic areas occupied by species change over ...

Pathophysiology Exam 1 Questions and Answers An ordered photographic display of a set of chromosomes from a single cell is a(n): A) metaphase spread. B) autosomal spread. C) karyotype. D) anaphase spread. - Answer-c An error in which homologous chromosomes fail to separate during meiosis is termed: A) aneuploidy. B) nondisjunction. C) polyploidy. D) anaplasia. - Answer-b A somatic cell that does not contain a multiple of 23 chromosomes is called: A) an aneuploid cell. B) a euploid c...

Multiple Myeloma Exam With Verified Solutions What is Multiple Myeloma? This is a bone marrow (B cell) cancer characterized by the proliferation of malignant plasma cells that can aggregate into tumor masses and then become distributed throughout the skeletal and organ systems resulting in multiple organ damage. What is a Plasma Cell? Immune cell that develops from a B-cell Secretes Antibodies malignant plasma cell Malignant plasma cells from one clone of B cells abnormally large...

_________ leads to the death of cells by damaging their DNA or interfering with DNA synthesis. Some also interfere with the functioning of the mitotic spindle. (anaphase) - chemotherapy _____________ is designed to prevent cells from receiving signals for continued growth and division - hormone therapy ____ arrested—does not go on to divide - G0 ____ is replicated before mitosis begins - DNA _____ is packaged into chromosomes. - DNA ______ Results in each chromosome being composed of tw...

Characteristics of Down Syndrome correct answers low nasal bridge -epicanthal folds -protruding tongue -low-set, flat ears -Poor muscle tone -short stature Patho Down Syndrome correct answers About 97% of cases are caused by nondisjunction during the formation of one of the parent's metes of during early embryonic development. The remaining 3% result from translocations. Cystic Fibrosis correct answers An autosomal recessive inherited disorder that is associated with defective epithelial ...

define one genetic map unit ~ the physical distance between two genes that results in a 1% frequency of recombination In birds, sex is determined by ZW chromosome inheritance. Males are ZZ and females are ZW. Within pigeon populations there is a recessive, Z-linked allele that is lethal in embryos. What is the expected sex ratio in the offspring of a cross between a male that is heterozygous for the lethal allele and a wildtype female? ~ 2:1 male to female A recessive allele on the X c...