Lipophilicity - Study guides, Class notes & Summaries

NUR 635 - Midterm Exam Study Guide.Latest Updates 2023 GCU NUR-635 Mid-Term Study Guide – Dr. Don Marsh - Pharmacology (from the Greek word ‘pharmakon,’meaning drug): the study of drugs and their structure, targets of action, mechanisms of action (MOA), distribution (how the body disburses them throughout the body), desired physiologic effects (efficacy) and undesirable side effects (toxicity). - Pharmacokinetics includes ADME (absorption, distribution, metabolism and elimination)...

What are two ways to overcome an infection with drug therapy? (List format) - Answer- 1. Bactericidal 2. Bacteriostatic What is chemotherapy? - Answer- Treatment of disease by chemicals (drugs) that have a specific toxic effect upon disease producing microorganisms, or that selectively destroy cancerous tissue What are the key targets of antibiotics? - Answer- Cell wall, ribosomes, DNA/RNA What are the most important drugs by class? - Answer- Beta-lactams What are bacteria cell wall...

Adrenergic agonists - ANS Drugs that stimulate and mimic the actions of the sympathetic nervous system Adrenergic receptors - ANS Receptor sites for the sympathetic neurotransmitters norepinephrine and epinephrine Alpha-adrenergic receptors - ANS A class of adrenergic receptors that are further subdivided into alpha1-and alpha2-adrenergic receptors Autonomic functions - ANS Bodily functions that are involuntary and result from the physiologic activity...

What are two ways to overcome an infection with drug therapy? (List format) - 1. Bactericidal 2. Bacteriostatic What is chemotherapy? - Treatment of disease by chemicals (drugs) that have a specific toxic effect upon disease producing microorganisms, or that selectively destroy cancerous tissue What are the key targets of antibiotics? - Cell wall, ribosomes, DNA/RNA What are the most important drugs by class? - Beta-lactams What are bacteria cell walls made of? - pept...

PCOL 355 E2 Exam Questions with Correct A An inert gas is needed for density measurements. a. True b. False - Answer-true The Compressibility Index and Hausner ratio of a pharmaceutical powder are identical. a. True b. False - Answer-false The bulk density and tapped density of a pharmaceutical powder are identical. a. True b. False - Answer-false The surface area and specific surface area of a pharmaceutical powder are identical. a. True b. False - Answer-false What is the key ...

What routes of med admin are parenteral - All Injections ( IM Sub Q IV, Intrathecal), AND Inhaled , transdermal (patches) , transmucosal (sublingual, nasal, rectal) . All PO meds = enteral; Topical is all ointments placed on the skin PO meds absorption pattern - Varies greatly due to: »»Stability and solubility of the medication »»Gastrointestinal pH and emptying time »»Presence of food in the stomach or intestines »»Other medications currently being administered »»Forms of med...

Pharmacology (from the Greek word ‘pharmakon,’meaning drug): the study of drugs and their structure, targets of action, mechanisms of action (MOA), distribution (how the body disburses them throughout the body), desired physiologic effects (efficacy) and undesirable side effects (toxicity). - Pharmacokinetics includes ADME (absorption, distribution, metabolism and elimination). - Absorption: absorption from the administration site either directly or indirectly into the blood/plas...

Phcy 401 – ADME Exam Study Guide. Pharmacokinetics - answerstudy of movement of drugs in body absorption - answermovement of drug from application site to blood stream distribution - answermovement of drug from blood stream to target metabolism - answertransformation, activation, detox of drug by enzyme excretion - answerelimination of drug from body hydrophilic - answerwater loving lipophilic - answerlipid loving hydrophobic - answerwater fearing lipophobic - answerlipid fearing log...

GMS6504 Exam 2 Questions With Correct Answers What 4 factors determine whether a drug is good or bad? - answer1. Lipinski's Rule of 5 2. Chemical Reactivity: Good or bad 3. Functional Groups 4. Drug Targets Name atleast 3 Lipinski's Rules (Basic) - answer1. Molecular mass greater than 500 Da 2. High Lipophilicity, LogP greater than 5 3. More than 5H bond donors (FH,NH,OH) 4. More than 10H bond acceptors (O,F,N) When we have high values of Lipinski's Rules of 5. what does this tell u...

Pharmacology exam 1 Questions with correct Answers When there is enough data to demonstrate the new drug safety and effectiveness researchers submit an investigational New Animal Drug application to the... After clinical trials, one files a New Animal Drug Application (NADA). FDA overseas on the use of controlled substances that are listed in schedule I - V. DEA it's a branch of pharmacology that studies the fate of pharmacological substances in the body their absorption, dist...