Aminopenicillins - Study guides, Class notes & Summaries

NR 566 / NR566 Advanced Pharmacology Final Exam Review | Rated A+ 2023 Complete Guide. When aminopenicillins are combined with beta-lactamase inhibitors - their spectrum in broadened • beta-lactamase inhibitors that can be combined with aminopenicillins - clavulanate, sulbactam, & tazobactam • Penicillinase-resistant penicillins drugs - Nafcillin - Oxacillin - Cloxacillin - Dicloxacillin - Methicillin • Penicillinase-resistant penicillins active against - Streptococcus, MSSA, so...

140 MUST KNOW NCLEX MEDS EXAM QUESTIONS WITH COMPLETE SOLUTIONS UPDATED 2024/2025 Alteplase (t-PA) class: thrombolytics Indication: MI, acute ischemic stroke, occluded central lines Action: converts plasminogen to plasmin which degrades the fibrin found Nursing Considerations: - contraindicated in active bleeding -monitor for anaphylaxis - use caution with uncontrolled hypertension Atorvastatin (Lipitor) class: lipid-lowering agent Indication: management of high cholesterol (hyperch...

Causes of drug resistance - correct answer People not completing their antibiotics/inappropriate use, overuse of broad spectrum ABO's Every ABO class has_____________________ - correct answer resistance organisms Vaccination with pneumococcal vaccine has - correct answer decreased resistance Inhibits the biosynthesis of peptidogylcan bacterial cel...

Penicillin G *** - ANSWER - First PCN given PO and IM - PO only about 1/3 of dose is absorbed - IM and IV are most effective (to get therapeutic serum level) (IM is painful) - primarily bactericidal Penicillin V *** - ANSWER - next type produced - 2/3 absorbed by GI tract, less patent than PCN G - It is effective against mild - moderate infections, including anthrax PCNS (structure) - ANSWER - beta-lactam antibiotics. - beta-lactam structure interferes with bacterial cell wall synth...

Penicillin G - First penicillin available for clinical use - Therapeutic Uses: bactericidal to gram positive and some gram negative - Best absorbed IM, worst is oral - Only potassium penicillin G can be given IV (concern for kidney/heart patients) - excreted by the kidney - minimal metabolism - risks in renal pts, acutely ill, elderly and infants - half life = 30 minutes - side effects = pain at site of IM injection, neurotoxicity (seizures), hyperkalemia (cardiac arrest), and necrosis of skin i...

Causes of drug resistance: - Answer-1.Recent use of antibiotics Overuse of broad-spectrum antibiotics 2.Age younger than 2 years or older than 65 years 3.Day-care center attendance 4.Exposure to young children 5.Multiple medical comorbidities 6.Immunosuppression Why is it important to vaccinate with pneumococcal vaccine? - Answer-Vaccination with pneumococcal vaccine has decreased resistance to antibiotics What class of antibiotics are the most effective? - Answer-Beta-lactam Beta lact...

NR 566 / NR566 Advanced Pharmacology Final Exam Review | Rated A+ 2023 Complete Guide. beta-lactamase inhibitors that can be combined with aminopenicillins - clavulanate, sulbactam, & tazobactam • Penicillinase-resistant penicillins drugs - Nafcillin - Oxacillin - Cloxacillin - Dicloxacillin - Methicillin • Penicillinase-resistant penicillins active against - Streptococcus, MSSA, some coagulase-negative staphylococci, peptostreptococcus • Anti-pseudomonal penicillin drugs - Pip...

USMLE Step 1 Antibiotics Quiz with complete solutions | Latest 2023/2024 Penicillin mechanism -- binds to penicillin binding proteins in peptidoglycan (blocks transpeptidase crosslinking); activates autolytic enzymes penicillin use -- gram positives and syphilis penicillin toxicity -- hypersensitivity reactions, hemolytic anemia penicillinase resistant penicillins -- methicillin, nafcillin, dicloxacillin penicillinase resistant penicillin use -- Staph aureus penicillin resistant penicill...

Who discovered the first antibiotic? - Alexander Fleming in 1928 What is the leading cause of antibiotic resistance? - Excessive and inappropriate use of antibiotic agents. What are risk factors for having a drug-resistant pathogen? - The leading risk factors include recent use of antibiotics, age younger than 2 or older than 65, day-care center attendance, exposure to young children, multiple medical comorbidities, recent hospitalization, and immunosuppression. How many antibiotic classes...

NU 641 Advanced Pharm for NPs Antibiotics Exam Questions with All Correct Answers Causes of drug resistance: - ANSWER 1.Recent use of antibiotics Overuse of broad-spectrum antibiotics 2.Age younger than 2 years or older than 65 years 3.Day-care center attendance 4.Exposure to young children 5.Multiple medical comorbidities 6.Immunosuppression Why is it important to vaccinate with pneumococcal vaccine? - ANSWER Vaccination with pneumococcal vaccine has decreased ...