Ost 575 - Study guides, Class notes & Summaries

OST 575 - Exam #2 --> Lower GI pharmacology Questions And Correct Answers What is the MOA of Metoclopramide? - answerantagonist at dopamine receptors *enhances effects of ACh at smooth muscle in GI tract* What effect does Metoclopramide have by blocking dopamine receptors in the chemoreceptor trigger zone of the area postrema? - answerproduces *antiemetic* action What are the adverse effects of Metoclopramide? - answerNervousness Drowsiness Dystonic reactions--> *parkisonian like ...

OST 575 - Exam #3 Questions And Correct Answers --> Hepatobiliary disorders I What is the process of cirrhosis? - answerinflammatory cells damage parenchyma--> parenchyma begins to collapse--> new collagen laid down, leads to scarring--> scar will bridge portal regions and central vein regions *leading to fibrosis/cirrhosis* What is the gross anatomy of someone with liver cirrhosis? - answerliver is smaller in weight distinct nodules are usually present texture is very firm ...

OST 575 - Exam #3 Questions And Correct Answers --> Understanding LFTs What are the enzyme tests for liver damage? - answerTransaminase (AST, ALT) Alkaline phosphatase gamma glutamyl transpeptidase (GGT) What lab levels are tested to determine how well the liver is functioning? - answerAlbumin Prothrombin time What can also be tested to detect if there is liver damage that is NOT an enzyme and can be detected based on physical presentation? - answerbilirubin What are some general sym...

OST 575 - Exam #3 Questions And Correct Answers --> Hepatobiliary Disorders II What is the blood supply of the liver? - answer*dual blood supply* from hepatic artery and portal vein What is the common reaction pattern that occurs when the biliary system undergoes dysfunction for any reason, causing buildup of bile and bile pigments? - answercholestasis What are some mechanisms that can cause cholestasis? - answerdecreased or defective bile secretion obstruction of bile channels, eithe...

OST 575 Exam 2 Drugs Questions And Correct Answers Metoclopramide MOA - answerDopamine receptor antagonist -Increases LES tone -Increases GI peristalsis Metoclopramide adverse effects - answer-Nervousness -Drowsiness -Dystonic reactions -Breast tenderness and galactorrhea Metoclopramide clinical uses - answer-Antiemetic for pt's undergoing chemo -GERD -Esophagitis Loperamide - answer-Opiate-like MOA -May cause constipation and toxic megacolon -Used for acute nonspecific diarrhea...

OST 575 - Exam #3 Questions And Correct Answers --> Cirrhosis. Distortion of the hepatic vasculature causing shunting of portal and arterial blood supply directly into hepatic outflow (central veins) and the compromise of exchange between hepatic sinusoids and the adjacent liver parenchyma (i.e hepatocytes) is characteristic of what liver disorder? - answerLiver cirrhosis What are the clinical consequences of liver cirrhosis? - answerimpaired *hepatocyte* function increased intrahepati...

©SIRJOEL EXAM SOLUTIONS 10/14/2024 11:14 PM OST 575 - Exam #2 Questions And Correct Answers --> Colon Cancer. What is the 2nd most common cancer in men and women in the US? - answercolon cancer What are patient controlled risk factors for colon cancer? - answerlack of exercise red meat obesity smoking alcohol use What is the most common type of colon cancer? what are the subtypes? - answerAdenocarcinoma 1. *mucinous mucus* (most common) 2. Signet ring cell Where does adenocarci...

OST 575 - Exam #3 Questions And Correct Answers --> Pancreatitis What is pancreatitis? - answeran inflammatory process of the pancreas with variable involvement of regional tissues or remote organ systems Why is incidence of pancreatitis in the US rising? - answerdue to biliary pancreatitis *obesity* What are the 3 criteria for diagnosis of pancreatitis? - answerSymptoms such as epigastric pain consistent with disease Serum amylase or lipase greater than 3x upper limits of normal Rad...

OST 575 - Exam #3 Questions And Correct Answers --> Pancreatic Cancer What is the prognosis of pancreatic cancer? - answerPOOR with overall 5 year survival of 5% What are the different parts of the pancreas? - answer What age does pancreatic cancer usually start to occur? - answerafter 45 yrs old (rare before) What race is pancreatic cancer more common in? - answerafrican americans What are the groups at risk for pancreatic cancer? - answerHistory of hereditary pancreatitis familial hi...

OST 575 - Exam #3 Questions And Correct Answers --> Liver Cancer. Where is primary cancer of the liver common? Who is it common in? - answerCommon in Asia and Africa *common in males* What are some chemicals that can cause primary cancer of the liver? - answeraflatoxin exogenous hormones methotrexate What are common causes of cirrhosis (that eventually will cause hepatocellular carcinoma)? - answerHemachromatosis Hepatitis B (*Asia, Africa*) Alcoholic Parasitic (Schistosomiasis) ...