Cooperativity Study guides, Class notes & Summaries

Ligand correct answers A molecule which is reversibly bound by a protein; A small molecule that binds specifically to a larger one; for example, a hormone is the ligand for its specific protein ligand. Induced Fit correct answers Proteins or enzymes may undergo conformational changes when a lignand binds which alters the function of the protein; What do Myoglobin and haemoglobin contain? correct answers They contain a hem prosthetic group which binds oxygen. What does Heme consist of? c...

Ways of regulating enzymes - correct answer allosteric effector competitive inhibition noncompetitive inhibition cooperativity Competitive inhibition - correct answer substance the enzyme by occupying the active site Noncompetitive inhibition - correct answer substance inhibits the enzyme by binding to a location other than the active site and changes the shape of the enzyme Cooperativity - correct answer enzyme becomes more receptive to additional substrates Ribosomes are...

Biochemistry NBME Exam 2024 Well Revised and Verified Answers Updated Proteoglycans Act as molecular sieves in ECM, CT, and cartilage GAGs are the long polysacc chains attached to core protein GAG is heavily hydrated and cushions (has "-" charge) Degraded via lysosomal pathway (defect = MPS) Glycolipids A.K.A. sphingolipids Made with ceramide lipid base Serine + palmitoyl-CoA => sphingosine (+FFA) => ceramide Carb part sticks out into ECM (same w/ glycoproteins) Side chain p...

VCU Biochem Exam 2 Questions And Answers is binding of ligands reversible? - ANS-yes, it is essential for it to be reversible cooperativity - ANS-In multisubunit proteins, conformational changes in one subunit can affect the others functions of globular proteins - ANS-1. storage of ions and molecules (myoglobin and ferritin) 2. transport of ions and molecules (hemoglobin, serotonin transporter) 3. defense against pathogens (antibodies, cytokines) 4. muscle contraction (actin, myosin) 5....

AQA AS Biology - Mass Transport 3.3.4 Questions & Answers 2024 What is the structure of haemoglobin? - ANS-A quaternary structure with 4 polypeptide chains (2 alpha, 2 beta) Each chain associated to a haem group containing an Fe2+ ion Each Fe2+ can carry one oxygen - hence Hb can carry a maximum of 4 oxygen What is the role of haemoglobin? - ANS-Transport oxygen around the body How does haemoglobin transport oxygen? - ANS-When ppO2 is high - at lungs - Hb has a high affinity for oxyge...

WGU C624 Biochemistry Module 3, Exam Questions and answers, 100% Accurate. VERIFIED. Describe the functions of hemoglobin and myoglobin. - -Hemoglobin transports oxygen, Myoglobin stores oxygen. The correct number of subunits, heme groups, iron and oxygen that bind to hemoglobin versus myoglobin. - -Hemoglobin has: 4 subunits 4 heme groups 4 iron molecules binds 4 molecules of oxygen. Myoglobin has: 1 subunit 1 heme group 1 iron molecule binds 1 molecule of oxygen. Cooperat...

ACS Biochemistry Exam Questions and Correct Solutions 2024 Describe the structural changes in hemoglobin that allow for cooperative binding of O2 - Answer - Binding of O2 in one subunit causes a conformational change in an adjacent subunit allowing O2 to bind Which amino acids in "a" would be charged at pH 7? - Answer -Asp, Glu, Arg, His, Lys Which amino acids are negatively charged? - Answer -Asp, Glu which amino acids are positively charged? - Answer -Arg, His, Lys How are beta sheets...

UNE Medical Biochemistry Exam 1 Questions With 100% Correct Answers what percentage of water is in the body? - answer60% Relationship between protons and acids & bases - answerAcids donate proton. Bases accept proton Strong Acids Vs Weak Acids - answerStrong acids fully dissociate (100%) and weak acids partially dissociate properties of water - answerdipole dipole polar H bonding dissolves electrolytes ( CL /Na) Small Kd- doesn't dissociate alot kw ion product - answer10^-14 pH - a...

Biochemistry NBME Exam 2024 Well Revised and Verified Answers Updated Proteoglycans Act as molecular sieves in ECM, CT, and cartilage GAGs are the long polysacc chains attached to core protein GAG is heavily hydrated and cushions (has "-" charge) Degraded via lysosomal pathway (defect = MPS) Glycolipids A.K.A. sphingolipids Made with ceramide lipid base Serine + palmitoyl-CoA => sphingosine (+FFA) => ceramide Carb part sticks out into ECM (same w/ glycoproteins) Side chain p...

Michaelis-Menten Kinetics Correct Answer [S] = Concentration of substrate V = Velocity Km is inversely related to the affinity of the enzyme for its substrate Vmax = Directly proportion to the enzyme concentration Most enzymatic reactions follow of hyperbolic curve [Michaelis-Menten] kinetics Enzymatic reactions that exhibit a sigmoid curve [Hemoglobin] exhibit positive cooperativity Lineweaver-Burk Correct Answer ↑ y-intercept, ↓ Vmax The further to the right, the x-intercept [Cl...