Chloramphenicol - Study guides, Class notes & Summaries

Erythromycin (Ans- 50S ribosome, inhibits TRANSLOCATION (movement of tRNA-aa from acceptor site to peptidyl site) clindamycin, chloramphenicol (Ans- 50 ribosome, inhibits PEPTIDYL TRANSFERASE (incorporation of new a.a.'s into growing strand) Linezolid (Ans- 50S protein synthesis inhibitor tetracycline (Ans- 30S ribosome, blocks tRNA-aa from binding to ACCEPTOR SITE on mRNA aminoglycosides (Ans- 30S ribosome, blocks INITIATION of translation and induces PREMATURE TERMINATIO...

What is antibiotic selection? Correct Answer-Survival of a population of antibiotic resistant cells within a larger population of antibiotic sensitive cells. Where can antibiotic selection occur? Correct Answer-Anywhere where there are antibiotics and bacteria present. The best-surviving bacteria will be selected for. Name a common use for antibiotic selection in microbiological research. Correct Answer-To identify and isolate cells that have piece of DNA of interest such as a particular p...

GMU Bio Diversity Exam 1 Review with Complete Solutions Actinobacteria -Filamentous bacteria (resemble fungi) -Not all have high GC content -Streptomyces spp. are an important source of many antibiotics (tetracycline, chloramphenicol, streptomycin, neomycin) -Mycobacterium tuberculosis and M. leprae pathogenic Actinobacteria -Generally not spore-forming (Streptomyces an exception), "gram-positive" but some have an outer membrane and stain variably; some contain mycolic acid in the ...

During what trimester is a pregnant woman most at risk for adverse drug reactions with potential long term consequences? - Answer 1st trimester (fetus most at risk d/t rapid growth) What is BEERS criteria? - Answer Recommendations of medications inappropriate for elderly (65 and older), prescriber ultimately decides What is the CYP450 (cytochrome P450) - Answer liver enzyme system where medications are metabolized, can either be inducers or inhibitors and create drug-drug interact...

What pack size of hydrocortisone cream is GSL? : 10g What pack size of hydrocortisone cream is P? : 15g What indication and duration is codeine specifically licensed for? : Mild to moderate pain for a max of 3 days From what age are chloramphenicol eye drops licensed? : 2 and above What is the max quantity of paracetamol and aspirin (non-effervescent) tablets allowed to be sold OTC? : 100 (although practically less can be sold due to pack size) What are the limitations on psuedoephed...

3 M/action of antibiotics - Inhibition of cell wall synthesis (peptidoglycan) Inhibition of protein synthesis (30s+50s) Interference of bacterial DNA (folic acid) What AB drug classes inhibit cell wall synthesis? - Bacitracin Penicillins Cephalosporins What AB drug classes inhibit protein synthesis? - buy AT 30, CEL at 50 Aminoglycosides + Tetracyclines: 30S Chloramphenicol, Erythromycin (macrocodes) , cLindamycin: 50S Which AB drug classes interfere with bacterial DNA? - Sulfonamides, ...

Jones disease in sheep is caused by... - correct answer mycobacterium paratuberculosis Os - correct answer left eye (oculus sinister) What morphine like substance found in the thalamus and hypothalamus acts like a natural analgesic? - correct answer Endorphin The MAC of an anesthetic agent will change for all of the following reasons except - correct answer Patients breed For which patients should mass induction and isoflurane be avoided? - correct answer Patients with impaired respi...

antibiotic- old and new definition CORRECT ANSWER - originally referred to any compound produced by one species of microbe that could kill or inhibit the growth of other microbes. -today the term is also used for synthetic chemotherapeutic agents that are clinically useful but chemically synthesized. Selective toxicity CORRECT ANSWER -a quality of an antibiotic - Antibiotic must selectively kill or inhibit the pathogen but not the host, How is selective toxicity possible? CORRECT ANSWE...

Test Bank for Basic and Clinical Pharmacology 15th Edition By Bertram G. Katzung Chapter 1-66 Complete Guide A+. 1. Introduction: The Nature of Drugs & Drug Development & Regulation 2. Drug Receptors & Pharmacodynamics 3. Pharmacokinetics & Pharmacodynamics: Rational Dosing & the Time Course of Drug Action 4. Drug Biotransformation 5. Pharmacogenomics 6. Introduction to Autonomic Pharmacology 7. Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs 8. Cholinoceptor-Blocking Drugs 9. Adrenoc...

A nurse is caring for a client who is to receive 1,500 mL of 0.9% sodium chloride IV over 8 hours. The nurse plans to use IV tubing with a drop factor of 10gtt/mL. How many gtt/min of IV fluid should the client receive? (Round your answer to the nearest whole number). - ANS 31gtt/min A nurse is assessing a client who is receiving chloramphenicol (Chloromycetin). Which of the following findings is an adverse effect of this medication? (adverse affect is thrombocytopenia) Ecchymosis Ototo...