Antimorphic - Study guides, Class notes & Summaries

WEEK 1 Walden 6501 advanced pathophysiology (genetics, cellular biology and tissue) Answered Correctly!! acrocentric refers to the terminal location of centromere on chromosomes 13, 14, 15, 21, and 22 allelic heterogeneity the situation in which multiple alleles at a single locus can produce one or more disease phenotypes. amorphic refers ro mutations that cause a complete loss of function for the respective gene, and therefore yield the same phenotype as a complete gene deletion. aneup...

5. You are studying a mutation in mice, which acts dominantly. Mice that have only one copy of the allele carrying this mutation have a kinky tail phenotype You identify the gene that the mutation affects and find that the codon that encodes the second amino acid in the predicted protein has been mutated to a stop codon. Would you characterize this mutation as a loss-of- function or a gain- of-function and what specific subtype (hypermorphic, antimorphic, etc. ) within these categories? Exp...

Description of loss of function and gain of function alleles with main examples. Explanation of incomplete dominance and codominance