And engraftment - Study guides, Class notes & Summaries

BMTCN TEST B ACTUAL QUESTIONS AND ANSWERS 2024 GRADED A+ Transplant-related toxicity is a barrier that contributes to the under utilization for which of the following diseases? A. Non-Hodgkin lymphoma B. Acute myeloid leukemia C. Sickle cell disease D. Neuroblastoma C. Sickle cell disease Despite success of HSCT in sickle cell disease, barriers to successful HSCT include lack of a suitable donor, transplant related toxicity and immunologic graft rejection. Which of the following ...

EAQ CHAPT 40: RBC WBC DISORDERS EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ What is the most important environmental risk for developing leukemia? 1 Direct contact with others with leukemia Incorrect 2 Family history 3 Living near high-voltage power lines Correct 4 Smoking cigarette 4 A patient with leukemia is undergoing hematopoietic stem cell transplantation using stem cells harvested from the patient prior to high-dose chemotherapy. Which type of transplantatio...

BMTCN Review Chapter 5 - Graft-Versus-Host Disease GVHD - correct answer Competent donor t-cells recognize antigens, mount immune response, and and attack recipient organs Classifications of GHVD - correct answer Acute Chronic Hyperacute Overlap Syndrome Acute GVHD - correct answer Generally occurs within first 100 days or nor meeting chronic criteria Presents as erythematous, maculopapular rash, nausea, vomiting, anorexia, profuse diarrhea, ileus, or cholestatic liver Chro...

BMTCN Ch 5 - GVHD overall incidence of GVH? - correct answer 20-80% mortality rates d/t GVH? matched sibling vs unrelated - correct answer 18 % matched ib 20% unrelated what is GVH? - correct answer T cells from the donor recognize the recipient's cells as foreign and attack how does classic acute GVH present - correct answer erythematous mac/pap rash nausea/vomiting/anorexia/profuse diarrhea/ileus cholestatic liver disease all within 100 days of transplant or DLI what is persi...

BMTCNExample of a myeloid cell - correct answer Monocyte Hematopoiesis occurs in which area? - correct answer bone marrow which which is true about innate immunity? - correct answer it's a natural process that uses phagocytes that release inflammatory mediators in response to infection or illness aquired immunity - correct answer the response of either B cells or T cells to antigens human leukocyte antigen - correct answer -proteins that reside on the surface of cells -self v. nons...

Immunoglobulins are secreted by which type of cell? A. B-lymphocyte B. Megakaryocyte C. T-lymphocyte D. Natural killer - Answer A. B-lymphocyte B lymphocytes synthesize and secrete immunoglobulins. Which portion of the immunoglobulin activates the complement pathway? A. MHC Class I B. Fab C. Fc D. MHC Class II - Answer C. Fc The Fc region activates the complement pathway. Which of the following is a class II HLA antigen? A. B B. DR C. A D. C - Answer B. DR HLA DR, DQ and DP are ...

BMTCN Ch 5 - GVHD overall incidence of GVH? - correct answer 20-80% mortality rates d/t GVH? matched sibling vs unrelated - correct answer 18 % matched ib 20% unrelated what is GVH? - correct answer T cells from the donor recognize the recipient's cells as foreign and attack how does classic acute GVH present - correct answer erythematous mac/pap rash nausea/vomiting/anorexia/profuse diarrhea/ileus cholestatic liver disease all within 100 days of transplant or DLI what is persi...

Types of SCT (3) -Allogeneic -Syngeneic -Autologous Stem Cell Sources (3) -Peripheral Blood (PBSCT) -Bone Marrow -Umbilical Cord (UCB) Specific Types of Allogeneic Transplant (6) -Syngeneic -Matched sibling/related -Mismatch related -Matched unrelated -Mismatched unrelated -Umbilical cord Syngeneic (source, advantages, disadvantages) -Identical twin -No need for immunosuppression, disease free source -No graft vs tumor effect Allogeneic (source, advan...

BMTCN Test C Myeloid progenitors give rise to which of the following types of cells during hematopoiesis? A. NK cells B. Plasma Cells C. Erythrocytes D. T lymphocytes - correct answer C. Erythrocytes Myeloid progenitors give rise to erythrocytes Which of the following would be an optimal donor choice for a 26-year-old Caucasian male with acute myeloid leukemia? A. A 35-year-old mother of four B. A 30-year-old male with a body mass index of 25 C. The patient's 14 year-old broth...

BMTCNExample of a myeloid cell - correct answer Monocyte Hematopoiesis occurs in which area? - correct answer bone marrow which which is true about innate immunity? - correct answer it's a natural process that uses phagocytes that release inflammatory mediators in response to infection or illness aquired immunity - correct answer the response of either B cells or T cells to antigens human leukocyte antigen - correct answer -proteins that reside on the surface of cells -self v. nons...