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BMTCN Test B Transplant-related toxicity is a barrier that contributes to the underutilization for which of the following diseases? A. Non-Hodgkin lymphoma B. Acute myeloid leukemia C. Sickle cell disease D. Neuroblastoma - correct answer C. Sickle cell disease Despite success of HSCT in...

BMTCN Test AImmunoglobulins are secreted by which type of cell? A. B-lymphocyte B. Megakaryocyte C. T-lymphocyte D. Natural killer - correct answer A. B-lymphocyte B lymphocytes synthesize and secrete immunoglobulins. Which portion of the immunoglobulin activates the complement pathway? ...

BMTCN StudyWhat are the two types of bone marrow? - correct answer Red bone marrow = creates red blood cells, white blood cells, and platelets. Found in long and flat bones. Yellow bone marrow and fat cells = produce fat, cartilage, and bone. Found in long bones What are the components of he...

BMTCN StudyMyeloid - correct answer erythrocyte, platelets, neutrophil, basophil, eosinophil, monoblastic, macrophage, monocyte lymphoid - correct answer pre- B cell, pre-t cell, plasma cell, natural killer cell, t lymphocyte innate immunity - correct answer occurs naturally- phagocytes releas...

BMTCN ReviewWhy are cell renewal mechanisms important? - correct answer Because of senescence, utilization, and emigration What is the objective of hematopoiesis? - correct answer Maintain peripheral blood with a constant level of different types of blood cells What is immune function partiall...

BMTCN Review Chapter 8 - Professional Practice Nursing Practice - correct answer Influenced by: Professional organizations (ANA, ONS) -Scope and standards of practice State boards of nursing Accreditation agencies -The Joint Commission (TJC) -Foundation for the Accreditation of Cellular...

BMTCN Review Chapter 7 - Survivorship IssuesSurvivors and Survivorship - correct answer An individual is considered a cancer survivor from the time of diagnosis through the balance of his/her life Survivorship is a distinct phase of the cancer experience Some patients do not embrace the term ...

BMTCN Review Chapter 5 - Graft-Versus-Host Disease GVHD - correct answer Competent donor t-cells recognize antigens, mount immune response, and and attack recipient organs Classifications of GHVD - correct answer Acute Chronic Hyperacute Overlap Syndrome Acute GVHD - correct answer G...

BMTCN Review Chapter 4 - Transplant Preparative Regimens, Cellular Infusion, Acute Complications, and EngraftmentTRANSPLANT PREP REGIMENS - correct answer Treatment leading up to transplant Acronyms: Ara-C BCNU BU Cy DLT SCT TBI - correct answer Cytarabine Carmustine Busulfan Cyclophosp...

BMTCN Review Chapter 2-Types of Transplants and Sources of Stem CellsTypes of SCT (3) - correct answer -Allogeneic -Syngeneic -Autologous Stem Cell Sources (3) - correct answer -Peripheral Blood (PBSCT) -Bone Marrow -Umbilical Cord (UCB) Specific Types of Allogeneic Transplant (6) - correc...

BMTCN Review Chapter 1-Basic Concepts and Indications for TransplantationGoal of Transplant - correct answer -Cure disease -Increase disease free survival Hematopoiesis - correct answer -Regulation, production and development of blood cells -Pluripotent Stem cells -Progenitor Stem Cells. -Mye...

BMTCN Review 2023-Amy Which of the following is an example of a myeloid cell? A. Thymus-derived cells (T cells) B. Bone marrow-derived cells (B cells) C. Monocytes D. Natural killer cells - correct answer C. Monocytes Several factors affect immune reconstitution following hematopoietic ste...

BMTCN Practice Test B Patients who have received an HSCT should receive which of the following annual immunizations? A. Yellow Fever B. Intranasal influenza C. Inactive influenza D. Live rotavirus - correct answer C. Inactive influenza is recommended yearly. What is an advantage of using umb...

BMTCN Practice Test A Which of the following medications should a patient taking cyclosporine avoid following an allogenic HSCT? A. Torsemide B. Bumetanide C. Spironolactone D. Furosemide - correct answer C. Patients taking cyclosporine should avoid potassium sparing diuretics such as spironola...

BMTCN Practice Questions (Review Manual and Cert Review)When a patient senses a leaking in IV site during a chemotherapy infusion, what does the nurse do first? A. Please warning signs across the area to alert others to the spill B. Restart chemotherapy with a new order C. Put on the right safety...

BMTCN Numbers to KnowLeukapheresis - Peripheral blood stem cell collection: goal # cells in adults vs. pediatrics, how much blood commonly processed - Bone marrow: goal # cells, how much marrow obtained - correct answer PBSCs: 5 x10^6 CD34+ cells per kg of recipient's body weight - Adults: 12-15...

BMTCN MedicationATG - correct answer Immune Suppressant. not recommended for reduced intensity regimens s/s pulm edema, hepatic dysfunction. Skin rash,joint pains(serum Sickness-TREATED WITH STEROIDS) Used before Allo for immunosuppression and later to treat GVHD. BCNU(carmustine) - correct...

Malignant diseases - correct answer Leukemias, lymphomas, dysplastic syndromes, proliferative syndrome Non-malignant diseases - correct answer Hemoglobinopathies, inadequate hematopoiesis, metabolic disorders, immune deficits Acute Lymphoblastic Leukemia - correct answer 1st = Allogeneic stem ...

BMTCN Free TestWhich of the following studies should be completed at regular intervals for a patient receiving long-term steroids? A. Positron emission tomography scan B. Magnetic resonance imaging C. Dual energy x-ray absorptiometry D. Computed tomography scan - correct answer C. Dual energy ...

BMTCN Exam anthracycline: examples & side effects - correct answer -doxorubicin, idarubicin, daunorubicin, mitoxantrone -associated with cardiac issues (CHF, cardiomyopathy, arrhythmias) foscarnet: indication + administration + key side effect - correct answer -antiviral (i.e. CMV treatment) -...

BMTCN Exam Practice QuestionsWhen a patient senses a leaking in IV site during a chemotherapy infusion, what does the nurse do first? A. Place warning signs across the area to alert others to the spill B. Restart the chemotherapy with a new order C. Put on the right safety gear D. Environment...

BMTCN Chapter 8 Professional Practice A patient with multiple myeloma is receiving high-dose melphalan. The nurse has the patient chew on ice during the infusion to reduce the risk of mucositis. This is an example of which of the following? A. A clinical trial B. Evidence-based practice C. Ou...

BMTCN Chapter 7 Surivorship IssuesWhat is a patient who received a T-cell-depleted transplant at risk for developing within the first year following transplant? A. Acute myeloid leukemia B. Breast cancer C. Basal cell carcinoma D. Post-transplant lymphoproliferative disorders - correct answer ...

BMTCN Chapter 6 Post-Transplant Issues Which of the following is NOT an identified risk factor associated with infection? A. Personal history of infection B. Type of transplantation (autologous or allogeneic) C. Myeloablative transplant D. None of the above - correct answer D. None of the a...

BMTCN Chapter 5 Graft-versus-Host DiseaseT.R. is a 28-year-old woman with acute myeloid leukemia in her second complete remission who is admitted for a matched unrelated allogeneic stem cell transplantation. Her conditioning regimen is as follows: Myeloablation (busulfan/cyclophosphamide) and imm...

BMTCN Chapter 4BCNU - correct answer Carmustine Causes DNA Cross links and strand breaks Inhibits DNA repair Crosses blood/brain barrier Need pre/post hydration BCNU Side Effects - correct answer N/V Infusion reactions nephrotoxicity (increased Crea & BUN) pulmonary - cough, dyspnea, tachy...

BMTCN Chapter 4: Transplant Preparative Regimens, Cellular Infusion, Acute Complications, and EngraftmentWhat is the most important rationale for giving total body irradiation in multiple fractions? A. It is easier for patients. B. It decreases short-term side effects. C. It decreases long-term s...

BMTCN Chapter 3 - Transplant IssuesS.J. is about to undergo leukapheresis in preparation for an autologous transplant. The nurse informs her that she may experience tingling in her lips and extremities during the procedure. Which statement best explains this symptom? A. Numbness and tingling are si...

BMTCN Chapter 2 - Types of Transplants and Sources of Stem Cells M.J. is to undergo an autologous transplant. From whom will he receive his stem cells? A. A matched related donor B. A matched unrelated donor C. An umbilical cord blood donor D. Himself - correct answer D. Himself P.F. has und...

BMTCN Chapter 1 red marrow - what does it make, and where? - correct answer produces hematopoietic stem cells that create RBC, WBC, platelets, found in long, flat bones yellow marrow - what does it make, and where? - correct answer produces stromal stem cells for fat, cartilage, nad bone, found ...

BMTCN Chapter 1 Basic Concepts and Indications for Transplantation Which of the following is an example of a myeloid cell? A. Thymus-derived cells (T cells) B. Bone marrow-derived cells (B cells) C. Monocytes D. Natural killer cells - correct answer C. Monocytes Several factors affect immune...

BMTCN ch.04 preparative regimens - correct answer aka conditioning regiment part of HSCT when tx malignant diseases goal: eradicate residual disease and/or provide immunosuppression to prevent graft rejection prepare receipients bone marrow to accept new donor cells examples of chemo - correc...

BMTCN ch.03pre-transplant workup/evaluation - correct answer -labs: CBC+diff, chems, hep B&C, HIV, human t cell leukemia virus type 1, CMV, HSV, VZV, pregnancy, ABO/RH-, HLA, serology, rapid plasma regain testing -organ function tests: EF>50%, echo, EKG -disease eval: BMBx, LP, CT, MRI, bone sc...

BMTCN Ch 5 - GVHD overall incidence of GVH? - correct answer 20-80% mortality rates d/t GVH? matched sibling vs unrelated - correct answer 18 % matched ib 20% unrelated what is GVH? - correct answer T cells from the donor recognize the recipient's cells as foreign and attack how does cla...

BMTCN 2021 Free Practice TestThe cluster of differentiation system is used to: a. classify cell surface proteins on leukocytes. b. identify different types of cytokines. c. crossmatch for blood product transfusion. d. measure immune function. - correct answer The cluster of differentiation syste...

bmtcn - practice test granulocytic cell types include - correct answer basophil, eosinophil & neutrophil strong predictor of relapse following an allo? - correct answer disease stage diagnostic test for ocular gvhd? - correct answer schirmers test s/s of ocular gvhd - correct answer allo r...

BMTCN - Chapters 7-8What has contributed to the increased number of HSCTs? - correct answer -Treatment of older recipients with reduced-intensity conditioning -Increased number of donors What are the 4 categories of second malignancies? - correct answer 1. Acute leukemia and MDS 2. Lymphoma, i...

BMTCN - Chapter 6What are the types of cardiac diseases common post HSCT? What conditioning medications can cause these diseases? - correct answer Cardiomyopathy, arrhythmias, congestive heart failure - high dose Cytoxan and radiation causes this HTN/Dyslipidemia: Immunosuppression meds HTN/...

BMTCN - Chapter 5 (intro and acute GVHD)What is graft vs host disease? - correct answer Donor T cells recognize antigens on cells in the recipients organs as foreign and mount an immunologic response What are the two categories of GVHD? What determines the category? - correct answer Acute and chr...

BMTCN - Chapter 5 (chronic GVHD) What is chronic GVHD? - correct answer Late complication of HSCT effecting quality of life, immune mediated disorder. Must have at least one diagnostic manifestation of chronic GVHD or at least one distinctive sign confirmed by lab test. It can involve one or mo...