Psychopharmacology notes

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Chapter 8 provides an extensive overview of the roles of the neurotransmitters glutamate and GABA in the central nervous system. It delves into these neurotransmitters' synthesis, release, and inactivation processes, emphasizing their critical functions in excitatory and inhibitory neural transmission, respectively. The chapter highlights the mechanisms of excitotoxicity caused by excessive glutamate stimulation, which can lead to neuronal damage and death. This phenomenon is implicated in vari...

Chapter 6 - Serotonin provides a comprehensive overview of serotonin, covering its synthesis, release, inactivation, and functional roles within the brain and body. The chapter begins with a detailed explanation of serotonin synthesis, emphasizing the conversion of tryptophan to serotonin through the action of specific enzymes like tryptophan hydroxylase (TPH) and aromatic amino acid decarboxylase (AADC). It highlights the importance of dietary tryptophan and discusses various factors affecting ...