Tufts - Study guides, Class notes & Summaries

24 year old female presents with hand pain and shiny skin on her arms and hands. Provocative cold environment and cryotherapy. X-ray shows erosions of distal tufts and calcinosis in hands. - correct answer -Scleroderma Scleroderma • Most likely differential diagnoses: - correct answer -1) Acro-Osteolysis 2) Calcinosis Cutis 3) Systemic Sclerosis Scleroderma Most likely associated signs: - correct answer -1) Raynaud's Phenomenon 2) Skin hardening 3) Increase ANA Scleroderma Mo...

Which of the following is a local anesthetic subject to inactivation by plasma esterases? a) procaine b) lidocaine c) prilocaine d) mepivacaine e) bupivacaine - procaine - only ester listed, rest are amides Procaine differs from lidocaine in that a) procaine is a p-aminobenzoic acid ester and lidocaine isn't b) lidocaine is meta-aminobenzoic acid ester and procaine isn't c) the duration of action of procaine is longer than that of an equal dose of lidocaine d) procaine hydrochlori...

Tufts Pharmacology;NBDE II Review Exam 2023 Questions and Answers with complete solution

Prilocaine can cause - ANSWER methoglobinemia Esther LAs. They are metabolized in the... - ANSWER Procaine, tetracaine, cocaine, benzocaine. Plasma What must be true for a LA to penetrate tissue membranes? - ANSWER Non-ionized (free base form) What drug can prolong the effect of Lidocaine? - ANSWER Propanolol (competes for metabolism in liver, slows heart)

Objections - concerns or questions raised by the buyer Handling objections - is nothing more than explaining relative value. Requires a positive attitude and a solution-orientation Needs - I Do Not Need the Product or Service I've Never Done It That Way Before Objections related to _____? Product - I Don't Like the Product or Service Features I Don't Understand I Need More Information Objections related to the _____? Source - I Don't Like Your Company I Don't Like YouObjections...

Prilocaine can cause - methoglobinemia Esther LAs. They are metabolized in the... - Procaine, tetracaine, cocaine, benzocaine. Plasma What must be true for a LA to penetrate tissue membranes? - Non-ionized (free base form) What drug can prolong the effect of Lidocaine? - Propanolol (competes for metabolism in liver, slows heart) High plasma levels of LA cause.....even higher plasma levels cause... - Depression of CNS Inhibitors....shuts down respiration This disease makes you more s...

List 3 esters - ANSWER Procaine Tetracaine Cocaine Where are amides metabolized? - ANSWER Liver Where are esters metabolized? - ANSWER Pseudocholinesterases in plasma What drug group has the most consistent drug structure? - ANSWER LA What LA causes methemoglobinemia? - ANSWER Prilocaine

Prazosin - ANSWER-HTN, alpha1 blocker, inhibits release of norepinephrine Methyldopa - ANSWER-HTN, acts centrally to stimulate alpha receptors Clonidine - ANSWER-HTN, stimulates alpha2 receptors in CNS Propranolol - ANSWER-HTN, nonselective beta blocker Metoprolol - ANSWER-HTN, selective beta1 blocker Hydralazine - ANSWER-HTN, directly acts to vasodilate vascular smooth muscle Chlorothiazide - ANSWER-HTN, diuretic, thiazide, when administered with digitalis, will increase penet...