AAB MT (Hematology)
Liberty University
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Exam (elaborations) AAB MT (Hematology)
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What is hemoglobin composed of? - ANSWER 4 heme, 4 iron, 4 globins 
What disorder does a defect in heme synthesis lead to? - ANSWER Porphyria 
Porphyria - ANSWER Deficiency in the enzymes of the porphyrin pathway leads to 
insufficient production of heme. The principal problem in these deficiencies is the 
accumulation of porphyrins, the heme precursors, which are toxic to tissue in high 
concentrations. 
What is methemoglobin? - ANSWER Methemoglobin is a form of hemoglobin that 
contains fe...
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Exam (elaborations) AAB MT (Chemistry)
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Which of the four elements in proteins differentiated this class of substances from 
carbohydrates and lipids? - ANSWER Nitrogen 
Which of the proteins is soluble in water? - ANSWER Albumin 
How are amino acids joined together to form a chainlike structure? - ANSWER Peptide 
bonding 
Proteins may become denatured when subjected to mechanical agitation, heat, or 
chemical treatment. What does denaturation of proteins refer to? - ANSWER Alteration 
of tertiary structure 
Which aminoacidopathy ...
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Exam (elaborations) AAB MT (Microbiology)
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What term describes the morphology of organisms that vary in shape and size? - 
ANSWER Pleomorphic 
Capsules are the basis of which test? - ANSWER Serotyping 
A mucoid colony on blood agar medium indicates that which of the following 
characteristics may be present? - ANSWER Organism has a capsule. 
What are dark staining granules called? - ANSWER Metachromatic 
Which of the following organisms are non-motile? - ANSWER Shigella and Klebsiella 
In the bacterial growth cycle, growth ceases becau...
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Exam (elaborations) AAB MT (GeneralOperations)
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What are four types of centrifuges commonly used in the clinical lab? - ANSWER 
Tabletop, Micro, High-Speed, and Ultra. 
What does the daily maintenance of a centrifuge commonly consist of? - ANSWER 
Cleaned with 10% bleach 
What does the periodic maintenance of a centrifuge commonly consist of? - ANSWER 
Speed check by tachometer 
What is the function of a centrifuge in the clinical lab? - ANSWER To separate 
substances based on density by centrifugal forces. 
What is the RCF formula? - ANS...
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Exam (elaborations) AAB MT (Immunology)
- Exam (elaborations) • 14 pages • 2023
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Which of the following is not an external defense mechanism of natural immunity that 
provides the human body with a defense against invading microorganisms? - ANSWER 
Bursa of Fabricius 
All of the following are external defense mechanisms of natural immunity that provides 
the human body with a defense against invading microorganisms - ANSWER Skin, 
mucus, and body fluids 
Having an elevated temperature during an infection is an example of what type of 
immunity? - ANSWER Innate immunity ...
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Exam (elaborations) AAB MT (BASICKNOWLEDGE)
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Most common analytical error - ANSWER not checking specimen's integrity 
most common post-analytical error - ANSWER clerical error 
how often a procedure be reviewed: - ANSWER every 2 years before inspection 
thermometers must be checked against NIST thermometer - ANSWER annually 
following equipment maintenance, when is QC suggested? - ANSWER After any 
preventative maintenance 
according to CLIA who is responsible for processing, testing, and reporting results? - 
ANSWER testing personnel 
...
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Exam (elaborations) AAB MT (Hematology)
- Exam (elaborations) • 4 pages • 2023
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Interferes w/ lymphocyte cell histogram - ANSWER NRBC 
Interferes w/ lymphocyte cell histogram - ANSWER Malaria 
Interferes w/ lymphocyte cell histogram - ANSWER Cryoglobulins 
Interferes w/ lymphocyte cell histogram - ANSWER Sickle cell anemia 
Interferes w/ lymphocyte cell histogram - ANSWER Bernnard Soulier syndrome 
Interferes w/ lymphocyte cell histogram - ANSWER Cold agglutinans 
Interferes w/ monocluear cell histogram - ANSWER Blasts 
Interferes w/ monocluear cell histogram - ANSWER Lymph...
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Exam (elaborations) AAB MT (Chemistry)
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What are the functions of proteins? - ANSWER -Transportation of metabolic 
substances. 
-Part of the cell membranes. 
-Part of hormones and receptors. 
-Components of Enzymes. 
Proteins are composed of: - ANSWER -Carbon 
-Oxygen 
-Hydrogen 
-Nitrogen (differentiates proteins from carbohydrates & lipids). 
-Sulfur 
*Proteins have a high molecular weight, making them good immunogens. 
What proteins are soluble? - ANSWER Albumin- Soluble in water 
Globulins- Soluble in dilute salt solutions 
...
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Exam (elaborations) AAB MT (BasicKnowledge)
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What agency approves new test methodologies, instruments, and reagents before they 
are available for purchase by consumers? - ANSWER FDA 
How often should biological safety hoods be inspected? - ANSWER Annually 
What is the minimum number of standards required for a standard curve? - ANSWER 3 
What is the maximum magnification using a brightfield microscope? - ANSWER 1000X 
What is the most accurate pipette for reconstituting control material? - ANSWER Glass 
volumetric pipettes 
Which unit o...
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Exam (elaborations) AAB MT (MolecularDiagnostics)
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This DNA amplification method amplifies the nucleic acid used as a probe? - ANSWER 
Ligase Chain Reaction (LCR) 
What enzymes are used in Ligase Chain Reactions? - ANSWER DNA polymerase and 
DNA ligase 
What is the function of DNA polymerase in Ligase Chain Reaction? - ANSWER Is used 
to initiate DNA polymerase. 
What is the key advantage of using Ligase Chain Reaction instead of Polymerase Chain 
Reaction? - ANSWER Better specificity 
How does Ligase Chain Reaction differ from Polymerase Ch...
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