NSG 511
Rush University
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Unfolding Case Study Part One: The Patient with Hypertension Pathophysiology Concepts:
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ypertension (primary, no discernible cause) and hyperlipidemia (LDL cholesterol especially) damage 
the arterial endothelium and lead to atherosclerosis. 
Atherosclerosis is a systemic disease of the major arterial systems: cerebral, coronary, and peripheral. 
Atherosclerosis narrows the artery, in this case the coronary artery, and decreases myocardial oxygen 
supply. This is complicated by anemia, which further decreases oxygen supply. 
Pharmacotherapy is directed at controlling hypertension (...
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