Rush University
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what is the difference between cardiac myocyte action potential and that of the 
CNS or ANS? 
 nerve cell action potential is very short 
 cardiac action potential is much longer 
 they are longer to have adequate filling time in order to get a good contraction for a 
reasonable bolus of blood 
 the only way this can happen is if the action potential is longer 
 this will also mean that the refractory period will be longer 
What are the 5 phases of the non-pacemaker action potential? 
 0 - dep...
Ginseng 
 taken for: 
 Nervousness, Agitation, Insomnia, Diarrhea, Headaches, Heart Palpitation 
 
 Do not take with MAO inhibitors. Can alter affects with heart medications. Can 
increase the risk of bleeding when taken with blood clotting drugs 
 CI: Neuro, Heart, MAO, bleeding, coag drugs 
Ma Huang (Ephedra) 
 Dangerously elevate blood pressure, stimulate heart rate, and CNS 
 Associated with stroke, MI, and death 
 Banned > 10 mg in U.S. with exception of traditional Asian medicine 
 Met...
Components of BMP 
 Na, K, BUN, CO2, BUN, Creat, Gluc, ClHyponatremia S/S 
 Nausea 
 Muscle cramps 
 Confusion 
 Muscular twitching, coma 
 Seizures 
 Headache 
hypernatremia s/s 
 You are 'fried' or S.A.L.T. 
 F - Fever (low grade), flushed skin 
 R - Restless (irritable) 
 I - Increased fluid retention and increased BP 
 E - Edema (peripheral and pitting) 
 D - Decreased urinary output, dry mouth 
 
 S = Skin flushed 
 A = Agitation 
 L = Low-grade fever 
 T = Thirst 
#Examify | #Online...
Pharmicodynamics 
 What the body does to a drug 
What is the advantage to expressing drug dose as a log? 
 -we can go from 0.01 ug to 100 ug in one graph 
 -it allows us to express drug doses across a very wide range 
 -it expands the concentration at the lower axis - our ability to look at the body's 
response at the lower doses - because all of the action is happening at the left side of 
the graph we want to be able to finely grade the graph on the side of the graph 
where the response ...
Ginseng 
 taken for: 
 Nervousness, Agitation, Insomnia, Diarrhea, Headaches, Heart Palpitation 
 
 Do not take with MAO inhibitors. Can alter affects with heart medications. Can 
increase the risk of bleeding when taken with blood clotting drugs 
 CI: Neuro, Heart, MAO, bleeding, coag drugs 
Ma Huang (Ephedra) 
 Dangerously elevate blood pressure, stimulate heart rate, and CNS 
 Associated with stroke, MI, and death 
 Banned > 10 mg in U.S. with exception of traditional Asian medicine 
 Met...
Epidemiology is defined as? 
(Ans- the study of the distribution and determinants of health-related states or events in specified populations and the application of this knowledge to the control of health problems 
 
What are the core Epidemiological Functions? 
(Ans- 
Surveillance 
Field Investigations 
Analytic Studies 
Evaluation 
Linkages 
Policy 
 
What type of science is Epidemiology? 
(Ans- Quantitative 
 
What does measurement focus on in Epidemiology? 
(Ans- Distribution and Determ...
Completed advanced pharmacology exam 2 notes/objectives
Completed exam objectives/study guides
Exam 3 Objectives completed Advanced pharmacology
define cell necrosis 
(Ans- 
- irreversible injury 
- rapid plasma membrane structure loss 
- organelle swelling 
- mitochondrial dysfunction 
 
what happens in cell necrosis 
(Ans- 
- cell membrane is ruptured 
- leakage of cell contents 
- ATP is lost 
- organelles swell 
- severe mitochondrial damage 
- local inflammation 
 
define apoptosis 
(Ans- programmed cell death; not associated with inflammation 
 
list the three mechanisms of apoptosis 
 (Ans- 
1. apoptosis triggered by inter...