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First Aid USMLE Step 1: Biochemistry Exam Study Questions and Answers
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First Aid USMLE Step 1: Biochemistry 
Exam Study Questions and Answers 
What is a nucleoside? 
What is a nucleotide? 
Which are the purines? 
Which are the pyrimidines? - ANSWER-Side = base + (deoxy)ribose [sugar] 
Tide = base + (deoxy)ribose [sugar] + phosphaTe 
*Which are the purines?* 
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"pure as gold" = Adenosine, Guanosine 
*Which are the pyrimidines?* 
"CUT the pyramid" = Cytosine, Ur...
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USMLE step 1 – biochemistry Exam Study Guide Solutions
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USMLE step 1 – biochemistry Exam Study 
Guide Solutions 
infant with somnolence, vomiting, cerebral edema, decreased BUN, hyperammonemia - ANSWER- 
ornithine transcarbamoylase deficiency 
infantile cataracts, doesn't track objects, absent social smile - ANSWER-galactokinase deficiency 
infantile cataracts, hepatomegaly, jaundice, failure to thrive - ANSWER-uridyltransferase deficiency 
causes of Down syndrome - ANSWER-1) meiotic nondisjunction (95%) 
2) unbalanced robertsonian translocation...
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USMLE Step 3 Study Guide Solutions
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USMLE Step 3 Study Guide Solutions 
Pseudogout associations - ANSWER-hemochromatosis, hyperparathyroidism, acromegaly, 
hypothyroidism 
Gout crystals - ANSWER-negatively birefringent needles 
Pseudogout crystals - ANSWER-positively birefringent needles 
Vasculitis associated with chronic Hep B - ANSWER-polyarteritis nodosa 
Vasculitis associated with chronic Hep C - ANSWER-cryoglobulinemia 
Best blood test for polyarteritis nodosa - ANSWER-There is none. Get abdominal angiography first, 
then bi...
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USMLE Step 1 - uWorld High Yield Notes Exam Study Questions and Answers
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USMLE Step 1 - uWorld High Yield Notes 
Exam Study Questions and Answers 
What are the two major microtubular motor proteins? Which does anterograde axonal transport, which 
does retrograde axonal transport? - ANSWER-Kinesin, Dynein 
Kinesin: Anterograde 
Dynein: Retrograde` 
What do you think, immunologically speaking, when you see someone with recurrent Neisseria 
infections? - ANSWER-Inability to form the membrane attack (MAC) complex 
this is a common complement deficiency 
What is the defec...
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FIRST AID USMLE STEP 1 – VITAMINS EXAM STUDY GUIDE SOLUTIONS
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FIRST AID USMLE STEP 1 – VITAMINS 
EXAM STUDY GUIDE SOLUTIONS 
Vitamin A (retinol) - Function - ANSWER-Antioxidant; constituent of visual pigments (retinal); 
essential for normal differentiation of epithelial cells into specialized tissue (pancreatic cells, mucus- 
secreting cells); prevents squamous metaplasia. Used to treat measles and acute promyelocytic leukemia 
(APL). 
Vitamin A (retinol) - Deficiency - ANSWER-Night blindness (nyctalopia); dry, scaly skin (xerosis cutis); 
corneal degen...
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USMLE Step 1 Rapid Review Study Guide Solutions
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USMLE Step 1 Rapid Review Study Guide 
Solutions 
Abdominal pain, ascites, hepatomegaly, (also high D dimer, CHF without JVD) - ANSWER-Budd-Chiari 
syndrome 
Achilles tendon xanthoma - ANSWER-Familial hypercholesterolemia 
Adrenal hemorrhage, hypotension, DIC - ANSWER-Waterhouse-Friderichsen syndrome 
(meningococcemia) 
Arachnodactyly, lens dislocation, aortic dissection, hyperflexible joints - ANSWER-Marfan's (fibrillin 
defect) 
Athlete with polycythemia - ANSWER-Erythropoietin injection 
B...
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USMLE Step 1 Rapid Review Study Guide Solutions
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USMLE Step 1 Rapid Review Study Guide 
Solutions 
abdominal pain, ascites, hepatomegaly - ANSWER-Budd-Chiari syndrome 
Familial hypercholesterolemia - ANSWER-achilles tendon xanthoma 
adrenal hemorrhage, hypotension, DIC - ANSWER-Waterhouse-Friderichsen syndrome 
biochemistry of Marfan's syndrome - ANSWER-fibrillin defect 
posthepatic venous thrombosis - ANSWER-Budd-Chiari syndrome 
Familial hypercholesterolemia biochemistry - ANSWER-decrease in LDL receptor signaling 
Waterhouse-Friderichsen...
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USMLE STEP 1 Neurology Exam Practice Questions and Answers
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USMLE STEP 1 Neurology Exam Practice 
Questions and Answers 
The notochord induces what to differentiate into what? - ANSWER-Induces overlying ECTODERM to 
differentiate into NEUROECTODERM and form NUERAL PLATE 
Neural plate then gives rise to? - ANSWER-Neural tube and neural crest cells 
Notochord becomes what? - ANSWER-Nucleus pulposus of the intervertebral disks in adults 
Alar Plate - ANSWER-Dorsal [Sensory] 
Same orientation as spinal cord 
Basal Plate - ANSWER-Ventral [Motor] 
Same orienta...
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Public health science USMLE step 1 Exam Practice Questions and Answers
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Public health science USMLE step 1 Exam 
Practice Questions and Answers 
What number is in the denominator for the RATE of divorce? - ANSWER-Per 100 marriages 
What number is in the denominator for the RATE of infant mortality? - ANSWER-Per 1000 live births 
What is the typical RATE given in epidemiology for most cases? - ANSWER-Per 100,000. 
What are most disease rates in the US for most all diseases? - ANSWER-Less than 50 per 100,000.... 
Almost ALL are below 100 per 100,000 
What is an INCIDE...
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USMLE Step 1 Biostatistics/Epidemiology Study Guide Solutions
- Exam (elaborations) • 6 pages • 2024
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USMLE Step 1 Biostatistics/Epidemiology 
Study Guide Solutions 
Sensitivity - ANSWER-TP / (TP + FN) 
Specificity - ANSWER-TN / (TN + TP) 
Positive Predictive Value - ANSWER-TP / (TP + FP) 
Negative Predictive Value - ANSWER-TN / (FN + TN) 
Incidence Rate - ANSWER-# of new cases in a certain time period / population that is at risk during 
that time period 
This looks at new incidences occurring during a time period 
Prevalence - ANSWER-# of existing cases / population at risk 
Looks at ALL curre...
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