Vdj recombination - Study guides, Class notes & Summaries

BIOL 537 EXAM 3 QUIZ and PAPER QUESTIONS AND ANSWERS What does an antibody look like? What part determines antigen specificity? - ANSHeavy chain, light chain, disulfide bonds in Y-shape; binding sites at tip have antigen specificity What is the B cell receptor? - ANS-Membrane bound IgM Which steps in antibody generation is controlled by alternative splicing? A) VDJ recombination B) changing from membrane bound to secrete IgM C) class switching D) affinity maturation - ANS-B) chang...

BIOL 5500 FINAL EXAM QUESTIONS AND ANSWERS CD3 Helps to send a signal from TCR into the T cell. Has epsilon and delta subunits CD4 T helper cell. Has different subsets CD8 killer T cell; proliferation via IL-2 CD18 adhesion molecule, deficiency causes leukocyte adhesion deficiency (LAD); PMN and monocytes stuck in bloodstream, preventing diapedesis CD25 alpha chain of IL-2 receptor, could help prevent autoimmune diseases CD28 involved in secondary activation cascade for T cells; ...

PCOL 838b EXAM 1 MHC Class I - Answer- display antigens from intracellular pathogens interact with CD8 expressed on ALL cells MCH Class II - Answer- display antigens from extracellular pathogens. interact with CD4 expressed on APCs humoral immunity - Answer- antibody-mediated immunity involves B cells cell-mediated immunity - Answer- type of immunity produced by T cells that attack infected or abnormal body cells isotype of antibody - Answer- determine...

Immunology Final Practice Terms in this set (105) Which of the following cells are derived from lymphoid progenitors? cytotoxic T cells dendritic cells What proteins are not apart of the membrane attack complex? C9 C5a C7 C5b C6 C5a A new virus emerges that blocks enzymatic activity of phospholipase C. Based on the pathways we learned, which of them would be affected by this inhibition? NFAT, Ap-1, and NFkB Good PAMP examples Endosomal viral ssRNA Bacterial lipopolysaccharides ...

1. B lymphocytes are made in the: A. blood stream. B. bone marrow. C. liver. D. thymus. E. totipotent cell. -answer Answer: B Section: Introduction Difficulty: 1 Hint: Location of B cell production from a HSC. 2. How long does B cell maturation from an HSC to a mature B cell take? A. 1 to 2 hours B. 1 to 2 days C. 1 to 2 weeks D. 1 to 2 months E. 1 to 2 years -answer Answer: C Section: Introduction Difficulty: 1 Hint: B cell will begin to secrete antibodies within a few da...

BIOL 5500 FINAL EXAM QUESTIONS AND ANSWERS CD3 Helps to send a signal from TCR into the T cell. Has epsilon and delta subunits CD4 T helper cell. Has different subsets CD8 killer T cell; proliferation via IL-2 CD18 adhesion molecule, deficiency causes leukocyte adhesion deficiency (LAD); PMN and monocytes stuck in bloodstream, preventing diapedesis CD25 alpha chain of IL-2 receptor, could help prevent autoimmune diseases CD28 involved in secondary activation cascade for T cells; ...

13: B Cell Development Exam Study Guide Solutions Antibody reaction to bacterial toxins - ANSWER-Cell with receptor for toxins interacts with bacterial toxins, resulting in specific antibody localization to site of infection Antibody reaction to bacteria in extracellular space - ANSWER-Macrophages interact with bacteria in extracellular space and specific antibodies are localized to the site of infection. Complement activation may also be included. B Cell Development: Phase I - ANSWER-Rep...

This document provides a comprehensive overview of both innate and adaptive immune responses. It details the different cell types involved in innate immunity, the components and mechanisms of pathogen recognition, and the role of key receptors and transcription factors. The document also contrasts the innate and adaptive immune systems, explaining the structure and function of antibodies, the process of V(D)J recombination, and the factors contributing to antibody diversity. Additionally, it cov...

Which of the following statements is NOT correct? A.) Sites where PRRs can be expressed include the cell surface, within endosomes, in the cytoplasm, and as secreted molecules that circulate the blood B.) DAMPs are released when host cells undergo necrosis C.) TLRs are a type of PRR that is expressed by all cells of the body D.) Signaling adaptors lead to the activation of different cellular responses after recognition of PAMPs by PRRs E.) PAMPs and DAMPs both alert the immune system t...