Diseases and disorders as a consequence of obesity? - CORRECT ANSWER✔✔- Type-2-
diabetes
CVD
cancer = colon and breast
joint disorder
sleep apnea
Gall bladder disease
which cancers are not highly correlated with obesity? - CORRECT ANSWER✔✔- prostate
and lung cancer
What is cancer? - CORRECT ANSWER✔✔- cell with a series of genetic mutations:
de-differentiates (loss of function)
proliferative (grows uncontrollably --> does not respond to stop signals)
cannot repair DNA
resistant to apoptosis
which 2 hormones promotes cancer? - CORRECT ANSWER✔✔- Insulin
estrogen
, How does insulin promote cancer? - CORRECT ANSWER✔✔- stimulates growth of cell +
suppresses apoptosis in colon
decreases SHBG release from liver
How does estrogen promote cancer? - CORRECT ANSWER✔✔- stimulates growth of breast
tumors in postmenopausal women
When bound: to sex hormone binding globulin (SHBG) --> less bioavailable does not
stimualte growth
when free floating -->more stimulation of cell growth
Estrogen's function in young women? - CORRECT ANSWER✔✔- Growth of breast tissue.
obesity causes this tissue to increase release of estrogen. What is this tissue called? -
CORRECT ANSWER✔✔- adipose tissue
What is gall bladder disease? - CORRECT ANSWER✔✔- excessive production of
cholesterol
deposition of SOLID cholesterol in gall bladder
also a consequence of rapid weight loss --> rapid loss of body fat increases cholesterol
synthesis.
What is sleep apnea? - CORRECT ANSWER✔✔- occluded breathing during sleep and
extreme fatigue during the day
due to accumulated fat in the neck area that compresses on airway--> block airflow
Name the 2 joint disorders that come with obesity? - CORRECT ANSWER✔✔-
Osteoarthritis
Gout
what is osteoarthritis? - CORRECT ANSWER✔✔- Breakdown of cartilage between joints --
> removes the shock absorber
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