NUR 100 PHARMACOLOGY UNIT 4
EXAM STUDY GUIDE
If a patient takes an aspirin once a day what is it for? and what is the dosage? - Antiplatelet
properties 81-325mg
If a patient is taking aspirin prn what is it for? - antiinflammatory, analgesic, antipyretic 325 mg
PRN
S/S Salicylate toxicity - Tinnitis, renal failure, vomiting, metabolic acidosis, respiratory alkalosis
When should you take aspirin if you also take NSAIDS? - 2 hours before
Contraindications for all NSAIDS? - GI disorders, recent PUD, severe anemia, vit k deficient
Contraindications for taking NSAIDS with ARBs an ACE? - incr risk renal failure
Contraindications for taking NSAIDS and glucocortacoids? - incr risk gastric ulcer (give with
PPI)
Contraindication for taking Dicolfenac (NSAID)? - incr LFTs
Contraindications for taking NSAIDS with Warfarin? - serious bleeding complications
NSAIDS contraindicated with what disease? - CV disease
Salicylates are indictated for prevention of ? - MI, CVA, TIA, Angina
Salicylates DOC for ? - RA, DJD, OA, GA
Diflunsial is an RX (salicylate/NSAID) given for? - mild to moderate pain, OA, RA
what is the indication for Misoprostol? (cytotec) - decr bleeding LT NSAID use
What are two risks with all NSAIDS? - MI and stroke
if you are having surgery when should you stop taking NSAIDS? - 1 week
what happens when you take sulfa drugs with Celebrex (NSAID)? - severe allergic action
, MOA for allopurinol (Zyloprim) anti-gout medication? - prevents uric acid production
what are two side effects with alloputinol (Zyloprim) anti-gout medication? - agranulocytosis,
SJS
what are two teaching guidelines for taking alloputinol (Zyloprim) anti-gout medication? - d/c
with rash, report bleeding
MOA for colchicine, anti-gout medication? - reduces inflammatory process
What are two side effects of colchicine, anti-gout medicine? - gu/gi bleeding, n/v/d
what are teaching guidelines for colchicine, anti-gout? - report signs of bleeding
MOA for probenecid, anti-gout medication? - incr secretion of uric acid
what is the benefit of taking probenecid with penicillin? - delays renal excretion of penicillan
contraindication with probenecid, anti-gout medicine? - renal impairment
what kind of drug is etanercept (Enbrel)? - disease modifying antirheumatic drug
indications for etenercept (Enbrel)? - RA and JRA
2 Nrg considerations for entercept (Enbrel)? - 1. avoid with live vaccinations, pain, itchy,
redness at injection site
1st generation antihistamines have what effect? - sedating
2nd generation antihistamines have what effect? - impairment equal to illegal blood alcohol level
MOA 1st generation antihistamines? - H1 receptors block histamine binding
S/S of 1st generation antihistamines? - flushing, edema, itchy/pain, mucous production
2 therapeutic uses for 1st generation antihistamines? - allergic reactions, motion sickness
Can you treat a common cold with antihistamines? - NO
SE of 1st generation antihistamines besides the common fatigue and N/V/D? - visual,
paradoxial excitement, confusion