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PCOL 824 Final Exam ACTUAL Exam Questions and CORRECT Answers $7.99   Add to cart

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PCOL 824 Final Exam ACTUAL Exam Questions and CORRECT Answers

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PCOL 824 Final Exam ACTUAL Exam Questions and CORRECT Answers serotonin receptor (5HT2C) - CORRECT ANSWER- serotonin binding activates the satiety pathway leptin - CORRECT ANSWER- -hormone produced in fat cells -stimulates the satiety pathway and inhibits the hunger pathway ghrelin - CORRE...

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  • October 12, 2024
  • 8
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • PCOL 824
  • PCOL 824
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MGRADES
PCOL 824 Final Exam ACTUAL Exam
Questions and CORRECT Answers
serotonin receptor (5HT2C) - CORRECT ANSWER✔✔- serotonin binding activates the
satiety pathway


leptin - CORRECT ANSWER✔✔- -hormone produced in fat cells
-stimulates the satiety pathway and inhibits the hunger pathway


ghrelin - CORRECT ANSWER✔✔- stimulates the NPY pathway (hunger)


amphetamine-like drugs - CORRECT ANSWER✔✔- -short term management of obesity
(appetite suppressant)
ADR: weight rebound


orlistat - CORRECT ANSWER✔✔- irreversible inhibitor of GI lipase (decreases fat
absorption)
ADR: oily spotting, flatulence, fecal urgency, oily stool, decreased absorption of fat soluble
vitamins


phentermine/topiramate - CORRECT ANSWER✔✔- appetite suppressant
*no rebound
ADR: fetal toxicity, SUICIDAL IDEATION, glaucoma, insomnia, increased HR and bp,
DSYGEUSIA (metal taste disturbance)


lorcaserin - CORRECT ANSWER✔✔- selective 5-HT2C receptor agonist
*rebound effect and weight loss plateau
ADR: HA, dizziness, nausea


bupropion/naltrexone - CORRECT ANSWER✔✔- antidepressant and opiate receptor
antagonist

, ADR: insomnia, SUICIDAL IDEATION, increased HR and bp, nausea, HA, dizziness, dry
mouth
*contraindicated in pts with opioid dependency


liraglutide - CORRECT ANSWER✔✔- GLP-1 mimetic
ADR: diarrhea, pancreatitis, N/V


cellulose-citric acid polymer - CORRECT ANSWER✔✔- hydrogel that takes up water and
expands with the stomach
*medical device
ADR: diarrhea, abdominal pain/distension, constipation


fenfluramine/dexfenfluramine - CORRECT ANSWER✔✔- *taken off the market
MOA: activation of 5-HT2C receptors
ADR: cardiac valvular fibrosis


phenylpropanolamine - CORRECT ANSWER✔✔- *taken off the market
MOA: amphetamine-like appetite suppressant
ADR: increased risk of hemorrhagic stroke


sibutramine - CORRECT ANSWER✔✔- *taken off the market
MOA: inhibitor of NEP and serotonin reuptake causing increased activation of 5-HT2C
ADR: increased HR and BP, serotonin syndrome


rimonabant - CORRECT ANSWER✔✔- *taken off the market
MOA: antagonist of cannabinoid CBI receptor (inhibits the hunger pathway-NPY)
ADR: psychiatric effects (depression)


pramlintide - CORRECT ANSWER✔✔- amylin analog
*decreases glucagon release, slows rate of gastric emptying, increases satiety

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