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USMLE Step 1-Mycology Question and Answer
Sabouraud's agar - Fungi 
 
Fungal spores - Most fungal spores are asexual. Both coccidioidomycosis and histoplasmosis are transmitted by inhalation of asexual spores. Conidia = asexual fungal spores (e.g., blastoconidia, athroconidia) 
 
Histoplasmosis - Dimorphic fungi that can cause systemic mycosis, endemic to Mississippi and Ohio river valleys. Causes pneumonia. In bird or bat droppings. Intracellular (tiny yeast inside macrophages [below]): <img src="158a - Histoplasmosis.JPG" /> ...
- Exam (elaborations)
- • 5 pages •
Sabouraud's agar - Fungi 
 
Fungal spores - Most fungal spores are asexual. Both coccidioidomycosis and histoplasmosis are transmitted by inhalation of asexual spores. Conidia = asexual fungal spores (e.g., blastoconidia, athroconidia) 
 
Histoplasmosis - Dimorphic fungi that can cause systemic mycosis, endemic to Mississippi and Ohio river valleys. Causes pneumonia. In bird or bat droppings. Intracellular (tiny yeast inside macrophages [below]): <img src="158a - Histoplasmosis.JPG" /> ...
USMLE Step 3 pt. 2 Question and Answer
what is the best initial thing to do in a patient with a hyperosmolar hyperglycemic state - aggressive volume resuscitation - they are generally severely volume depleted 
 
then IV insulin 
 
*avoid management of hyperkalemia because these guys usually have a total body potassium deficit 
 
what can occur in patients with poorly controlled diabetes - hyperosmolar hyperglycemic state (HHS) or DKA 
 
describe Hyperosmolar hyperglycemic state (HHS) - -likely in DM T2 
-negative serum ketones (which...
- Exam (elaborations)
- • 2 pages •
what is the best initial thing to do in a patient with a hyperosmolar hyperglycemic state - aggressive volume resuscitation - they are generally severely volume depleted 
 
then IV insulin 
 
*avoid management of hyperkalemia because these guys usually have a total body potassium deficit 
 
what can occur in patients with poorly controlled diabetes - hyperosmolar hyperglycemic state (HHS) or DKA 
 
describe Hyperosmolar hyperglycemic state (HHS) - -likely in DM T2 
-negative serum ketones (which...
UWorld & NBME Practice Tests Question and Answer
Fetal hydantoin syndrome - D/t use of phenytoin or other anti-epileptic (*valproic acid, carbamazepine*), which can cross the placenta, generating *low folate* and high oxidative metabolites. 
 
Results in *cleft lip and palate, wide anterior fontanelle, distal phalange hypoplasia, cardiac anomalies, neural tube defects, microcephaly*, causing developmental delay and poor cognitive outcomes. 
 
Of these risks, *neural tube defects* is the *greatest*. 
 
Fetal alcohol syndrome - Can present w/ mi...
- Exam (elaborations)
- • 25 pages •
Fetal hydantoin syndrome - D/t use of phenytoin or other anti-epileptic (*valproic acid, carbamazepine*), which can cross the placenta, generating *low folate* and high oxidative metabolites. 
 
Results in *cleft lip and palate, wide anterior fontanelle, distal phalange hypoplasia, cardiac anomalies, neural tube defects, microcephaly*, causing developmental delay and poor cognitive outcomes. 
 
Of these risks, *neural tube defects* is the *greatest*. 
 
Fetal alcohol syndrome - Can present w/ mi...
NBME 4 step 3 practice exam Question and Answer
65 yo F has a 3 month hx of *increasing low back pain*. Had low back pain for past 3 yrs that's been treated w/NSAIDs and codeine. Now rated as 7/10 in severity. Pain radiates to both legs, worsens when walking or standing & Relieved when sitting. 1 YEAR AGO: X ray lumbosacral spine: mild osteoarthritis. Exam: 4/5 mm strength LE, hyporeflexia of knees&ankles b/, unsteady gait b/c of pain. No other abnormalities. Most appropriate diagnostic study of lumbosacral spine to order at this time? - *MR...
- Exam (elaborations)
- • 14 pages •
65 yo F has a 3 month hx of *increasing low back pain*. Had low back pain for past 3 yrs that's been treated w/NSAIDs and codeine. Now rated as 7/10 in severity. Pain radiates to both legs, worsens when walking or standing & Relieved when sitting. 1 YEAR AGO: X ray lumbosacral spine: mild osteoarthritis. Exam: 4/5 mm strength LE, hyporeflexia of knees&ankles b/, unsteady gait b/c of pain. No other abnormalities. Most appropriate diagnostic study of lumbosacral spine to order at this time? - *MR...
USMLE Step 1 Rapid Review Question and Answer
Abdominal pain, ascites, hepatomegaly, (also high D dimer, CHF without JVD) - Budd-Chiari syndrome 
 
Achilles tendon xanthoma - Familial hypercholesterolemia 
 
Adrenal hemorrhage, hypotension, DIC - Waterhouse-Friderichsen syndrome (meningococcemia) 
 
Arachnodactyly, lens dislocation, aortic dissection, hyperflexible joints - Marfan's (fibrillin defect) 
 
Athlete with polycythemia - Erythropoietin injection 
 
Back pain, fever, night sweats, weight loss - Pott's (TB to the vertebrae) 
 
Bi...
- Exam (elaborations)
- • 17 pages •
Abdominal pain, ascites, hepatomegaly, (also high D dimer, CHF without JVD) - Budd-Chiari syndrome 
 
Achilles tendon xanthoma - Familial hypercholesterolemia 
 
Adrenal hemorrhage, hypotension, DIC - Waterhouse-Friderichsen syndrome (meningococcemia) 
 
Arachnodactyly, lens dislocation, aortic dissection, hyperflexible joints - Marfan's (fibrillin defect) 
 
Athlete with polycythemia - Erythropoietin injection 
 
Back pain, fever, night sweats, weight loss - Pott's (TB to the vertebrae) 
 
Bi...
USMLE Practice Questions- AMBOSS Question and answer
A 25-year-old man comes to the physician because of persistent, high-pitched ringing noises in his ears. He has also been losing his balance lately. A CT scan of the head shows bilateral tumors involving the vestibulocochlear nerve. Which of the following chromosomes contains the tumor suppressor gene most likely to be involved in this case? 
 
 3p 
 5q 
 13q 
 17q 
 22q - E)22q 
 
The patient has bilateral acoustic neuromas, probably due to neurofibromatosis type 2, an autosomal dominant inheri...
- Exam (elaborations)
- • 14 pages •
A 25-year-old man comes to the physician because of persistent, high-pitched ringing noises in his ears. He has also been losing his balance lately. A CT scan of the head shows bilateral tumors involving the vestibulocochlear nerve. Which of the following chromosomes contains the tumor suppressor gene most likely to be involved in this case? 
 
 3p 
 5q 
 13q 
 17q 
 22q - E)22q 
 
The patient has bilateral acoustic neuromas, probably due to neurofibromatosis type 2, an autosomal dominant inheri...
Step2 CK NBME Practice Tests Question and Answer
Night incontinence without urge = - overflow incontinence (T2DM) 
 
Alcoholic cirrhosis AST/ALT, ALkPhos, GGT, bili, PT, albumin - AST/ALT 2:1 (not >500) 
AlkPhos mildly elevated 
GGT very elevated 
bilirubin elevated (conjugated > unconjugated) 
+/- bandemia, thrombocytopenia 
increased PT 
decreased albumin 
 
Who gets pneumococcal vaccine? - >65 
immune compromised (cirrhosis) 
 
HTN emergency medication - nitroprusside 
 
hyphema - blood in anterior eye 
 
hypopyon - inflammatory ce...
- Exam (elaborations)
- • 3 pages •
Night incontinence without urge = - overflow incontinence (T2DM) 
 
Alcoholic cirrhosis AST/ALT, ALkPhos, GGT, bili, PT, albumin - AST/ALT 2:1 (not >500) 
AlkPhos mildly elevated 
GGT very elevated 
bilirubin elevated (conjugated > unconjugated) 
+/- bandemia, thrombocytopenia 
increased PT 
decreased albumin 
 
Who gets pneumococcal vaccine? - >65 
immune compromised (cirrhosis) 
 
HTN emergency medication - nitroprusside 
 
hyphema - blood in anterior eye 
 
hypopyon - inflammatory ce...
NBME practice exams Question and Answer
Wide pulse pressure and bounding peripheral pulses - PDA 
 
Echo findings in dilated cardiomyopathy - Diffuse hypokalemia and dilation of the ventricles 
 
Causes of dilated cardiomyopathy - Viral illness, alcohol, ischemia 
 
Tx for life threatening hyperkalemia - Calcium chloride or calcium gluconate 
 
X-ray finding doe ankylosing spondylitis - Narrowing or sclerosis of the SI joints 
 
Cause of amenorrhea is bleeding occurs after progesterone challenge - Anovulation 
 
Treatment for SIADH - ...
- Exam (elaborations)
- • 2 pages •
Wide pulse pressure and bounding peripheral pulses - PDA 
 
Echo findings in dilated cardiomyopathy - Diffuse hypokalemia and dilation of the ventricles 
 
Causes of dilated cardiomyopathy - Viral illness, alcohol, ischemia 
 
Tx for life threatening hyperkalemia - Calcium chloride or calcium gluconate 
 
X-ray finding doe ankylosing spondylitis - Narrowing or sclerosis of the SI joints 
 
Cause of amenorrhea is bleeding occurs after progesterone challenge - Anovulation 
 
Treatment for SIADH - ...
USMLE Step 2 practice test 2 Question and Answer
12079. Characteristics of a galactocele? - May occur weeks to months after cessation of breastfeeding and is due to ductal blockage with resulting milk accumulation. Exam shows a soft, mobile, nontender mass. Dx is made by US and needle aspiration (also curative). 
 
12289. What might occur by treating pts with right sided HF (possibly due to COPD) with IV furosemide? - This will improve symptoms. However, you will get depletion of intravascular volume from diuresis. This can lead to AKI (BUN/Cr...
- Exam (elaborations)
- • 6 pages •
12079. Characteristics of a galactocele? - May occur weeks to months after cessation of breastfeeding and is due to ductal blockage with resulting milk accumulation. Exam shows a soft, mobile, nontender mass. Dx is made by US and needle aspiration (also curative). 
 
12289. What might occur by treating pts with right sided HF (possibly due to COPD) with IV furosemide? - This will improve symptoms. However, you will get depletion of intravascular volume from diuresis. This can lead to AKI (BUN/Cr...
USMLE step 2 practice exam 1 Question and Answer
patients blood smear shows that he has small hyper chromic red cells, without central pallor. this is called______ and what is another issue they will likely have? - speherocytes 
gallstones 
 
this HIV drug gives people bad dreams, dizzy, poor sleep, anxiety... - Efafirenz 
 
abacavir side effect - abacavir 
 
someone has urge incontinence. what is initial treatment? - frequent voluntary voiding 
 
pt on sumatriptan for migraine, what else should she NOT take - -ergots 
both are 5-ht agonists, ...
- Exam (elaborations)
- • 3 pages •
patients blood smear shows that he has small hyper chromic red cells, without central pallor. this is called______ and what is another issue they will likely have? - speherocytes 
gallstones 
 
this HIV drug gives people bad dreams, dizzy, poor sleep, anxiety... - Efafirenz 
 
abacavir side effect - abacavir 
 
someone has urge incontinence. what is initial treatment? - frequent voluntary voiding 
 
pt on sumatriptan for migraine, what else should she NOT take - -ergots 
both are 5-ht agonists, ...