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Impacts of the COVID-19 Pandemic on Mental Health
Suicidal ideations, elevated levels of substance abuse, prolonged distress, depression and anxiety disorders bring into the limelight concerns brought by a pandemic. During the Covid-19 pandemic approximately four out of ten adults in the United States reported symptoms of depressive and anxiety disorders. Long periods of isolation and job loss brought a lot of fear, worry, stress and uncertainty. A tracking poll dating back to July 2020, pointed that 32% of adults in the United States had insom...
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- • 6 pages •
Suicidal ideations, elevated levels of substance abuse, prolonged distress, depression and anxiety disorders bring into the limelight concerns brought by a pandemic. During the Covid-19 pandemic approximately four out of ten adults in the United States reported symptoms of depressive and anxiety disorders. Long periods of isolation and job loss brought a lot of fear, worry, stress and uncertainty. A tracking poll dating back to July 2020, pointed that 32% of adults in the United States had insom...
Paroxetine’s Pharmacokinetic and Pharmacodynamic Factors
Paroxetine is characterized as an antidepressant whose properties are induced by selective inhibition of serotonin uptake. The phenylpiperidine (trans-isomeric) has a low affinity for receptors – muscarinic receptors – translating to non-direct interaction with monoamine receptors which are also neurotransmitters. Paroxetine is actively absorbed in the gastrointestinal tract and undergoes a first pass metabolism leading to its reduced bioavailability. After transformation (in the liver), par...
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- • 4 pages •
Paroxetine is characterized as an antidepressant whose properties are induced by selective inhibition of serotonin uptake. The phenylpiperidine (trans-isomeric) has a low affinity for receptors – muscarinic receptors – translating to non-direct interaction with monoamine receptors which are also neurotransmitters. Paroxetine is actively absorbed in the gastrointestinal tract and undergoes a first pass metabolism leading to its reduced bioavailability. After transformation (in the liver), par...