Tufts pharmacology exam Study guides, Class notes & Summaries

a. Procaine Ester local anesthetic, along with tetracaine and cocaine All others are Amides Which of the following is a local anesthetic subject to inactivation by plasma esterases? a. Procaine b. Lidocaine c. Prilocaine d. Mepivacaine e. Bupivacaine

Which of the following is a local anesthetic subject to inactivation by plasma esterases? a) procaine b) lidocaine c) prilocaine d) mepivacaine e) bupivacaine - ANSWER procaine - only ester listed, rest are amides

Prilocaine can cause - ANSWER methoglobinemia Esther LAs. They are metabolized in the... - ANSWER Procaine, tetracaine, cocaine, benzocaine. Plasma What must be true for a LA to penetrate tissue membranes? - ANSWER Non-ionized (free base form) What drug can prolong the effect of Lidocaine? - ANSWER Propanolol (competes for metabolism in liver, slows heart)

List 3 esters - ANSWER Procaine Tetracaine Cocaine Where are amides metabolized? - ANSWER Liver Where are esters metabolized? - ANSWER Pseudocholinesterases in plasma What drug group has the most consistent drug structure? - ANSWER LA What LA causes methemoglobinemia? - ANSWER Prilocaine

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Tufts Pharmacology;NBDE II Review Exam 2023 Questions and Answers with complete solution

Tufts Pharmacology NBDE Part II UPDATED Exam Questions and CORRECT Answers Prazosin - Correct Answer- HTN, alpha1 blocker, inhibits release of norepinephrine Methyldopa - Correct Answer- HTN, acts centrally to stimulate alpha receptors Clonidine - Correct Answer- HTN, stimulates alpha2 receptors in CNS Propranolol - Correct Answer- HTN, nonselective beta blocker Metoprolol - Correct Answer- HTN, selective beta1 blocker