Sherpath pharmacodynamics - Study guides, Class notes & Summaries

If a patient receives an average effective dose (ED₅₀) at initial treatment and shows signs of toxicity, which action by the health care provider should the nurse anticipate? - Reduce the dosage. The ED50 is defined as the dose that is required to produce a defined therapeutic response in 50% of the population. Patients who show signs of toxicity will need a dosage reduction. The patient read that a new medication has a high therapeutic index, and asks the nurse what that means. How sh...