Prescribing sbom Study guides, Class notes & Summaries

acute testing - usually single dose study causes of confusion in the elderly - - sepsis - 'something in the head'- tumour, CVA, subdural, meningitis - medication - metabolic: dec Na, dec glucose, AKI chronic testing - Repeated doses for 1-2 yrs; used to investigate carcinogenicity clinical trials: phase 1 - Define route & metabolic fate in normal volunteers (n<50). Initial dose: usually 1/20th or 1/50th of effective dose in animals. ADR monitored by clinical biochemistry etc clinic...

if a patient needs IV fluids for routine maintenance alone, how much fluid do they need? - Answer 25-30 ml/kg/day how much electrolytes are needed per day? - Answer 1 mmol/kg/day (K+ Na+ Cl-) how much glucose is needed per day? - Answer 500-100g/day (to limit starvation ketosis) how is fluid lost everyday? - Answer - insensible losses e.g. sweat/breath (500ml/day)