Pk exam 2 - Study guides, Class notes & Summaries
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PK Exam 2 2023 with 100% correct answers
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Start of clearance concepts 
 
 
 
** Elimination/Clearance of a drugs is primarily mediated through what 2 things? 
Metabolism and excretion 
 
 
 
** Clearance (CL) can be used to describe 
the process of drug elimination from the body (as an alternative to the word elimination). 
 
also represents a PK parameter that allows quantification of the speed at which a drug is eliminated from the body. 
 
 
 
What does CL allow you to do? 
o Decide how much drug should be administered 
o How frequen...
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Kansas MPJE Exam 2023 Study guide.
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Kansas MPJE Exam 2023 Study guide. 
When does a pharmacist license need to be renewed in KS? - ANSWER Biennially, 
June 30th 
What are the CE requirements in KS? - ANSWER 30hours /2years, board 
approved, this number is prorated for the year that you are a new grad 
Intern hour requirement in KS? - ANSWER 1740 hours 
Intern license expiration in KS? - ANSWER 6 years 
Regulations on the sale of pseudoephedrine containing products specific to 
Kansas? - ANSWER Must be 18 or over to purchase 
Purch...
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PK Exam 2 2023 with 100% correct answers
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Which one of the following is the best definition of Clearance? 
a. Non-reversible removal of active drug from the systemic circulation 
 
b. Pre-systemic loss of active drug 
 
c. Steady target plasma concentration range 
 
d. Conversion of the administered drug into active drug 
A 
 
 
 
When a drug is converted to an inactive metabolite, it is considered to be cleared. 
T/F 
True 
 
 
 
You read that a drug is in the ECCS Class 1A. Therefore, you can predict that drug is absorbed by__________...
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APK EXAM 2 STUDY GUIDE WITH COMPLETE SOLUTION!!
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APK EXAM 2 STUDY GUIDE WITH COMPLETE SOLUTION!!
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Pk exam 2 2023 with 100% correct answers
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T/F Drug transfer is typically reversible or passive in transfer. 
True! 
 
 
 
Drug distribution refers to 
reversible transfer of drug between blood and extra vascular fluids and tissue of the body 
 
 
 
The extent and rate of distribution is dependent upon 
the ______ characteristics of the ______ 
and 
the _____ characteristics of the _____ 
physiological characteristics of the tissue 
and 
physicochemical characteristics of the drug 
 
 
 
Drug distribution driven by two main concepts: 
Ra...
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PK Exam 2 2023 with 100% correct answers
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____________ is the physiological effect of the drug on the body. 
 
- Efficacy 
- Toxicity 
Pharmacodynamics 
 
 
 
____________ = minimum concentration required for the drug to be effective in 50% of the population 
Minimum effective concentration 
 
 
 
____________ - minimum concentration required to produce toxic effects in 50% of the population 
minimum toxic concentration 
 
 
 
____________ = range between the MEC and MTC 
therapeutic window 
 
 
 
____________ = the ratio between MTC:ME...
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PECT Special Education Mods 1&2 pk-8 exam 2024 with 100% correct answers
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PECT Special Education Mods 1&2 pk-8 exam 2024 with 100% correct answers
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NAPLEX CPK Exam 2024
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NAPLEX CPK Exam 2024 
Relistor - methylnaltrexone 
Movantik - naloxegol 
Kadian - morphine 
MS Contin - morphine 
Duramorph - morphine injection 
Tapentadol -
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APK ENHANCEMENT III EXAM 2023
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APK ENHANCEMENT III EXAM 2023...
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PK Exam 2 2023 with 100% correct answers
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Pharmacodynamics 
what the drug does to the body 
 
 
 
Pharmacokinetics 
what body does to the drug 
 
 
 
2D6 SUBSTRATES 
SPARTEINE & BUFURALOL 
 
 
 
2D6 INHIBITORS 
QUINIDINE 
 
 
 
2D6 INDUCERS 
NK 
 
 
 
2C8 SUBSTRATES 
PACLITAXEL & REPAGLINIDE 
 
 
 
2C8 INHIBITORS 
MONTEKULAST (SINGULAIR) 
 
 
 
2C8 INDUCER 
RIFAMPICIN 
 
 
 
2A6 SUBSTRATES 
NICOTINE & COUMARIN 
 
 
 
2A6 INHIBITORS 
METHOXSALEN & TRANYLCYPROMINE 
 
 
 
2A6 INDUCERS 
PHENOBARBATOL 
 
 
 
2C9 SUBSTRATES 
TOLBUTAMIDE, S-WA...
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