Pceut 531 ophthalmic - Study guides, Class notes & Summaries
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PCEUT 531 - Ophthalmic, Nasal, Inhalation and Rectal Administration questions with correct answers
- Exam (elaborations) • 6 pages • 2024
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PCEUT 531 - Ophthalmic, Nasal, Inhalation and Rectal Administration questions with correct answers
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PCEUT 531 - Ophthalmic, Nasal, Inhalation and Rectal Administration questions with correct answers
- Exam (elaborations) • 6 pages • 2023
- Available in package deal
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- $12.99
- + learn more
obstacles to delivery to anterior eye - Answer -spillage during instillation 
-lacrimal drainage 
-tear dilution 
-systemic absorption 
-corneal barriers to drug diffusion 
-enzymatic breakdown of drugs 
-binding of drug by uveal pigment 
 
problems with use of conventional eye drops - Answer -typical drop is 20-50uL but precorneal fluid space only ~7-10uL > excess drop volume rolls down cheek or exits through nasolacrimal duct allowing systemic absorption 
-ocular residence is relatively...
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