P gp inducers - Study guides, Class notes & Summaries

Common CYP Inhibitors G: Grapefruit Pacman: Protease Inhibitors (ritonavir) Azole antifungals: Fluconazole, ketoconazole, ect. Cyclosporine Macrolides: Clarithromycin, erythromycin, not azith Amiodarone Non-DHP CCBs: Dilt and verap CYP Inducers Phenytoin Smoking Phenobarbital Oxacarbazepine Rifampin Carbamazepine St. John's wort P-gp Substrate Antiocoags: apixaban, edoxaban CVD Drugs: digoxin, dilt, carvedilol Immunosuppressants: cyclosporine, sirolimus, tacroli...

MRA recommendation for CHF 1. symptomatic HFrEF </= 35% 2. Post-MI with </=40% and either HF symptoms or DM MRA CI 1. eGFR <30 2. SCr >/=2.5 in male, >/=2.0 in female 3. K >5.0 4. pt already on combination therapy with ACEI + ARB (d/t increase risk of hyperkalemia with MRA) Hydralazine/isosorbide recommended for which CHF patients? 1. AA patients with NYHA class III/IV taking ACEI/ARB , BB +/- MRA 2. any symptomatic HFrEF patients who are intolerant to ACE...

What are the 3 ways that drugs can be eliminated kidneys (urine) gallbladder (bile) gut (feces) What are the 2 ways that inducers induce CYP enzymes increase the expression of the gene sequence that codes for the enzyme (makes more of the enzyme present) increasing the activity of the enzyme (making it work faster) Enzyme inhibition occurs _____ and typically takes _____ to see effect. The same is true for its offset. fast; at most a few days Enzyme induction occurs __...

NAPLEX Final Exam Questions & Answers 2022 Common CYP Inhibitors - ANSWERSG: Grapefruit Pacman: Protease Inhibitors (ritonavir) Azole antifungals: Fluconazole, ketoconazole, ect. Cyclosporine Macrolides: Clarithromycin, erythromycin, not azith Amiodarone Non-DHP CCBs: Dilt and verap CYP Inducers - ANSWERSPhenytoin Smoking Phenobarbital Oxacarbazepine Rifampin Carbamazepine St. John's wort P-gp Substrate - ANSWERSAntiocoags: apixaban, edoxaban CVD Drugs: digoxin, dilt,...

Immunoglobulin brands - ANSWER--Gammagard -Octagam -Privigen -Carimune NF -Flebogamma DIF -Gamunex-C Live attenuated flu vaccine - ANSWER-FluMist Quadrivalent Tdap - ANSWER--Adacel -Boostrix DTaP/Hep B/IPV - ANSWER-Pediarix Hep A vaccine - ANSWER--Havrix -VAQTA Hep B vaccine - ANSWER--Engerix-B -Heplisav-B -Recombivax HB Inactivated trivalent flu vaccine - ANSWER--Fluzone high dose -Fluad Inactivated quadrivalent flu vaccine - ANSWER--Afluria -fluarix -flulaval ...

Common CYP Inhibitors - CORRECT ANSWER-G: Grapefruit Pacman: Protease Inhibitors (ritonavir) Azole antifungals: Fluconazole, ketoconazole, ect. Cyclosporine Macrolides: Clarithromycin, erythromycin, not azith Amiodarone Non-DHP CCBs: Dilt and verap CYP Inducers - CORRECT ANSWER-Phenytoin Smoking Phenobarbital Oxacarbazepine Rifampin Carbamazepine St. John's wort P-gp Substrate - CORRECT ANSWER-Antiocoags: apixaban, edoxaban CVD Drugs: digoxin, dilt, carvedilol Immunosuppr...

NAPLEX Exam Review Questions and answers, rated A+ Common CYP Inhibitors - -G: Grapefruit Pacman: Protease Inhibitors (ritonavir) Azole antifungals: Fluconazole, ketoconazole, ect. Cyclosporine Macrolides: Clarithromycin, erythromycin, not azith Amiodarone Non-DHP CCBs: Dilt and verap CYP Inducers - -Phenytoin Smoking Phenobarbital Oxacarbazepine Rifampin Carbamazepine St. John's wort P-gp Substrate - -Antiocoags: apixaban, edoxaban CVD Drugs: digoxin, dilt, carvedilol Immun...

NAPLEX Exam Review Questions and answers, rated A+ Common CYP Inhibitors - -G: Grapefruit Pacman: Protease Inhibitors (ritonavir) Azole antifungals: Fluconazole, ketoconazole, ect. Cyclosporine Macrolides: Clarithromycin, erythromycin, not azith Amiodarone Non-DHP CCBs: Dilt and verap CYP Inducers - -Phenytoin Smoking Phenobarbital Oxacarbazepine Rifampin Carbamazepine St. John's wort P-gp Substrate - -Antiocoags: apixaban, edoxaban CVD Drugs: digoxin, dilt, carvedilol Immun...

Common CYP Inhibitors - Answer G: Grapefruit Pacman: Protease Inhibitors (ritonavir) Azole antifungals: Fluconazole, ketoconazole, ect. Cyclosporine Macrolides: Clarithromycin, erythromycin, not azith Amiodarone Non-DHP CCBs: Dilt and verap CYP Inducers - Answer Phenytoin Smoking Phenobarbital Oxacarbazepine Rifampin Carbamazepine St. John's wort P-gp Substrate - Answer Antiocoags: apixaban, edoxaban CVD Drugs: digoxin, dilt, carvedilol Immunosuppressants: cyclospor...

Common CYP Inhibitors correct answer: G: Grapefruit Pacman: Protease Inhibitors (ritonavir) Azole antifungals: Fluconazole, ketoconazole, ect. Cyclosporine Macrolides: Clarithromycin, erythromycin, not azith Amiodarone Non-DHP CCBs: Dilt and verap CYP Inducers correct answer: Phenytoin Smoking Phenobarbital Oxacarbazepine Rifampin Carbamazepine St. John's wort P-gp Substrate correct answer: Antiocoags: apixaban, edoxaban CVD Drugs: digoxin, dilt, carvedilol Immunosuppr...