Lipinski parameters - Study guides, Class notes & Summaries

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GMS 6504 Exam Questions and Answers 100% Correct
  • GMS 6504 Exam Questions and Answers 100% Correct

  • Exam (elaborations) • 13 pages • 2024
  • GMS 6504 Exam Questions and Answers 100% CorrectGMS 6504 Exam Questions and Answers 100% CorrectGMS 6504 Exam Questions and Answers 100% CorrectGMS 6504 Exam Questions and Answers 100% CorrectLipinski's rule of 5 - ANSWER-- Poor absorption or permeation are more likely when: 1. mass greater than 500 Da 2. highly lipophilic - logP > 5 3. more than 5 hydrogen bond donors 4. more than 10 hydrogen bond acceptors Partition coefficient - ANSWER-p = C(octanol)/C(water) - ratio of the equili...
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GMS 6504 Exam Questions and Answers 100% Correct
  • GMS 6504 Exam Questions and Answers 100% Correct

  • Exam (elaborations) • 13 pages • 2024
  • GMS 6504 Exam Questions and Answers 100% CorrectGMS 6504 Exam Questions and Answers 100% CorrectGMS 6504 Exam Questions and Answers 100% CorrectGMS 6504 Exam Questions and Answers 100% CorrectLipinski's rule of 5 - ANSWER-- Poor absorption or permeation are more likely when: 1. mass greater than 500 Da 2. highly lipophilic - logP > 5 3. more than 5 hydrogen bond donors 4. more than 10 hydrogen bond acceptors Partition coefficient - ANSWER-p = C(octanol)/C(water) - ratio of the equili...
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GMS 6504 Exam Questions and Answers 100% Correct!!
  • GMS 6504 Exam Questions and Answers 100% Correct!!

  • Exam (elaborations) • 13 pages • 2024
  • Lipinski's rule of 5 - ANSWER-- Poor absorption or permeation are more likely when: 1. mass greater than 500 Da 2. highly lipophilic - logP > 5 3. more than 5 hydrogen bond donors 4. more than 10 hydrogen bond acceptors Partition coefficient - ANSWER-p = C(octanol)/C(water) - ratio of the equilibrium concentrations of dissolved substance in a two-phase system containing two largely immiscible solvents (water & octanol) - Log10(P) Improved Lipinski Parameters - ANSWER-1. Partition...
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GMS6504/GMS 6504 University Of Florida -GMS 6504 CHAPTER 4 Questions With Complete Solutions
  • GMS6504/GMS 6504 University Of Florida -GMS 6504 CHAPTER 4 Questions With Complete Solutions

  • Exam (elaborations) • 13 pages • 2024
  • GMS6504/GMS 6504 University Of Florida -GMS 6504 CHAPTER 4 Questions With Complete Solutions
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GMS 6504 Exam With Questions And Accurate Answers 2024-2025
  • GMS 6504 Exam With Questions And Accurate Answers 2024-2025

  • Exam (elaborations) • 19 pages • 2024
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