Kuby immunology ch 2 test - Study guides, Class notes & Summaries

Define stem cells. - ANSWER Ability to regenerate or "self-renew" Ability to differentiate into all diverse cell types Describe hematopoiesis. - ANSWER Formation and development of blood cells What cell type gives rise to all blood cells? - ANSWER Hematopoietic stem cell (HSC) Why is the study of hematopoiesis difficult? - ANSWER Because there is roughly 1 HSC per 50,000 cells in bone marrow, HSC function decreases with age, "Lin" markers found on mature cells Undifferentiated cells l...

These are specialized sites in the gut and other mucosal tissues that coordinate the encounter of antigen with antigen-specific lymphocytes and their development into effector and memory cells. ex. spleen, lymph nodes - ANSWER secondary lymphoid organs These organs (thymus and bone marrow) regulate the development of immune cells from immature precursors. - ANSWER primary lymphoid organs It gives rise to all functionally specialized, mature blood cells (red blood cells, granulocytes, macro...

primary lymphoid organs - ANSWER organs in which lymphocyte precursors mature into antigenically committed , immunocompetent cells. In mammals, the bone marrow and thymus are the these organs in which B-cell and T-cell maturation occur, respectively. secondary lymphoid organs - ANSWER organs and tissues in which mature, immunocompetent lymphocytes encounter trapped antigens and are activated into effector cells. In mammals, the lymph nodes, spleen, and mucosal-associated lymphoid tissue (MA...

effector response - ANSWER elimination or neutralization of the invader memory response - ANSWER a more rapid and heightened immune reaction upon later attack innate immunity - ANSWER molecular and cellular mechanisms predeployed before an infection and poised to prevent or eliminate it