Bch4024 test 1 questions - Study guides, Class notes & Summaries
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BCH4024 TEST 1 QUESTIONS WITH COMPLETE SOLUTIONS
- Exam (elaborations) • 16 pages • 2024
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BCH4024 TEST 1 QUESTIONS WITH COMPLETE SOLUTIONS 
diffusion-limited process: - Answer-reaction rate is determined by how fast reactants collide 
 
the Protonation and deprotonation of macromolecules? - Answer-acid/base groups on surface react immediately 
 
acid/base groups deep inside may never ionize 
 
hydrogen bonds of buried helices and beta-sheets require the "conformation breathing" -local unfolding 
 
Pepsin - Answer-a digestive enzyme secreted into gastric juice, having a pH of 1.5 a...
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BCH4024 TEST 1 QUESTIONS WITH COMPLETE SOLUTIONS
- Exam (elaborations) • 17 pages • 2024
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BCH4024 TEST 1 QUESTIONS WITH COMPLETE SOLUTIONS 
Isoelectric Point of Amino Acids - Answer-At the isoelectric point (pI = pH), average charge equals 0 
The Henderson-Hasselbalch Eqn. can be applied at pI for both equilibrium dissociations. 
 
Two dissociation reactions involve the net zero charge species HAH+ <--> HA + H+ 
 HA <--> A- + H+ 
 
(Isoelectric Point of Amino Acids) 
Two Henderson-Hasselbalch equations 
can be summed to solve for pI. - Answer-2pI=pKa1+ pKa2 +log [HA] +log...
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