Alpha thalassemia - Study guides, Class notes & Summaries

NR507/ NR 507 Midterm Exam (New 2024/ 2025 Update) Advanced Pathophysiology | Questions and Verified Answers| 100% Correct | A Grade – Chamberlain QUESTION The patient with sickle cell anemia is at high risk for stroke Answer: True QUESTION Cells that contain abnormal types of hemoglobin are more susceptible to infection by the parasite that causes malaria Answer: False QUESTION Which of the following statements are correct regarding thalassemia ...

An 18-year-old G1P0 woman is seen in the clinic for a routine prenatal visit at 28 weeks gestation. Her prenatal course has been unremarkable. She has not been taking prenatal vitamins. Her pre-pregnancy weight was 120 pounds. Initial hemoglobin at the first visit at eight weeks gestation was 12.3 g/dL. Current weight is 138 pounds. After performing a screening complete blood count (CBC), the results are notable for a white blood count 9,700/mL, hemoglobin 10.6 g/dL, mean corpuscular volume ...

USMLE Step 3 exam 2024 When would you order a head CT with or without contrast? - correct answer With - looks for abscesses or intracranial masses WITHOUT - looks for acute bleeding which appears white. Contrast also appears white and can obscure bleeding. Like in intracranial hemorrhage Parents bring teen daughter to ED for cutting herself. No intent to commit suicide per daughter. Does she require hospitalization while you work her up for safety reasons? - correct answer NO. There ...

Autosomal Dominant 1 parent has, 50% change of child having Autosomal Recessive Both parents are carriers, 25% change of child having, 50% chance child is a carrier. Cystic Fibrosis affects pancreas causing secretions in lungs 21st Trisomy Down Syndrome Klinefelter Syndrome (XXY) male has extra X, female like qualities Turner Syndrome Missing X in females Alpha Thalassemia inherited blood disorder; mild to severe anemia Beta Thallasemia lo...

Diabetic skin manifestations are called? acanthosis nigricans Why do we give prostaglandins in HF, for kids? To keep the patent ductus arteriosus open until surgery What are nontender small erythematous lesions (macular, papular, or nodular) on the palms associated with infective endocarditis? Janeway Lesions What is Desferal used for? Beta Thalassemia (drug that chronically-transfused pts use to remove excess Iron from their bodies. Iron overload is therefore the leading cause of death a...

Which of the following statements about Alpha-Thalassemia is false? It is a condition where hemoglobin contains only beta subunits. This disease is caused by a large DNA deletion between the HBA2 gene and the LUC7L gene. The LUC7L gene is transcribed in the same direction as the HBA2 gene. RNAi mechanisms result in the HBA2 gene getting silenced by DNA methylation.

PATHOLOGY HIGH YIELD NBME ELABORATED QUESTIONS AND REVIEWED ANSWERS 2023/2024 Anticentromere antibodies - CORRECT ANSWER-Scleroderma (CREST) Antidesmoglein (epithelial) antibodies - CORRECT ANSWER-Pemphigus vulgaris (blistering) Anti-glomerular basement membrane antibodies - CORRECT ANSWER-Goodpasture's syndrome (glomerulonehpritis and hemoptysis) Antihistone antibodies - CORRECT ANSWER-Drug-induced SLE (hydralazine, isoniazid, phenytoin, procainamide) Anti-IgG antibodies - CORRE...

Genetic Counseling Boards study guide (latest updates) *Sickle Cell* Genetics Phenotype Diagnosis Treatment - *Genetics:* HbSS Gluexon6Val mutation in HBB gene chr. 11p15.4 *Phenotype:* Structurally abnormal Hb Manifests at 6-12 months (HbF --> HbA) Painful crises, anemia, organ damage, pulmonary HTN *Diagnosis:* Hb electrophoresis *Treatment:* hydroxyurea (stimulates HbF) *Alpha-thalassemia* Genetics Phenotype - *Genetics:* 2 alpha globin genes (4 alleles) chr. 16 *Phe...

Anemia can contribute to: coronary ischemia Composition of blood 5.5L total. 50-55% = plasma; 90% water Erythropoesis is stimulated by... erythropoetin Hemoglobin A the majority of adult hemoglobin. 97% of circulating hemoglobin. 2 alpha and 2 beta chains. HbA2 minor adult hemoglobin. 2-3% of circulating hemoglobin. 2 alpha and 2 delta chains. Hemoglobin F Fetal hemoglobin. 2 alpha and 2 gamma chains. Has a greater affinity for and more regularly binds O2...

Family Medicine EOR Hematology Exam Questions and Verified Answers| 100% Correct (Latest 2023/ 2024 Update) Q: What is a common cause of sideroblastic anemia? Answer: Lead poisoning Q: What are neurological symptoms of lead poisoning? Answer: Ataxia Fatigue Learning disabilities Difficulty concentrating Developmental delays Peripheral neuropathy Q: What are other symptoms of lead poisoning? Answer: Anemia Colic, loss of appetite Proteinuria, glycosuria ...