Allhat trial - Study guides, Class notes & Summaries

The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial—Lipid Lowering Trial (ALLHAT LLT) compared 40 mg/d of pravastatin with usual care among 10,355 men and women aged 55 years or older with stage 1 or 2 hypertension, at least one additional coronary heart disease risk factor, and low-density lipoprotein (LDL) cholesterol levels of 120 to 189 mg/dL. After a mean of 4.8 years of treatment and follow-up, the difference in total cholesterol between the two...

MKSAP 19 Questions & Answers Correct Review Solution A+ 1) Adults with stage 1 hypertension who have an estimated 10-year atherosclerotic cardiovascular disease event risk of <10% should be managed with ____ - Correct Ans-nonpharmacologic therapy 2) Adults with stage 1 hypertension who have an estimated 10-year atherosclerotic cardiovascular disease event risk of ≥10% should be managed with ____ - Correct Ans-nonpharmacologic therapy & antihypertensive 3) Initial pharmacologic the...

CARDIOVASCULAR Renal: Diuretics: most act by disrupting solute reabsorption. NA and CH are predominant solutes in the filtrate. Most of these solutes is reabsorbed in PCT. Also, most bicarb and potassium is reabsorbed here also. Urine moves down loop of Henle and drawn into the interstitial space, thereby decreasing volume of tubular urine and causes the urine to become more concentrated. Diuretics work by blocking reabsorption of sodium and chloride. This creates osmotic pressure within the nep...