2 pcol 838b gi disease ii - Study guides, Class notes & Summaries

what are the roles of the lower esophageal sphincter in achalasia and in reflux esophagitis achalasia: a motor disorder; lower esophageal sphincter (LES) fails to relax properly; leads to dysphagia (difficulty swallowing), regurgitation and chest pain; over time leads to esophagus enlargement reflux esophagitis: increased frequency of LES relaxations; increased acidity; decreased LES tone leading to inflammation and burning chest pain at night or after meal due to repetitive acid exposure to e...