Poor metabolizers - Study guides, Class notes & Summaries

NR546 Midterm Exam 2023/2024 Questions And Answers Update A+. What should the PMHNP consider when prescribing chemical restraints? - Answer-- allergy status -prior med hx for adverse drug reactions r/t the meds ordered in the chemical restraint -state regulations regarding chemical restrains must be reviewed Are the PMHNP and other staff liable if the client has an allergic reaction or adverse side effects to the drugs used for chemical restraint? - Answer-No. The client has been court-or...

NR546 Midterm Exam 2023/2024 Questions And Answers Update A+. What should the PMHNP consider when prescribing chemical restraints? - Answer-- allergy status -prior med hx for adverse drug reactions r/t the meds ordered in the chemical restraint -state regulations regarding chemical restrains must be reviewed Are the PMHNP and other staff liable if the client has an allergic reaction or adverse side effects to the drugs used for chemical restraint? - Answer-No. The client has been court-or...

1. T/F - Both genetic and environmental factors influence individual response to, and tolerability of, psychotropic agents. True 2. T/F - FDA approved psychotropics are similar in overall effectiveness for their indicated disorder. True 3. The dopamine systems highly relevant to psychiatry include: a. Nigrostriatal i. Degeneration leads to Parkinson's ii. Drugs that inhibit dopamine here cause EPS b. Mesocorticolimbici. Reward pathway (addiction) ii. Target of antipsychotic properties (...

Genetic polymorphisms account for differences in metabolism, including: 1. Poor metabolizers, who lack a working enzyme 2. Intermediate metabolizers, who have one working, wild-type allele and one mutant allele 3. Extensive metabolizers, with two normally functioning alleles 4. All of the above Correct Answer 4. All of the above Up to 21% of Asians are ultra-rapid 2D6 metabolizers, leading to: 1. A need to monitor drugs metabolized by 2D6 for toxicity 2. Increased dosages ne...

G-Protien coupled receptors and how they interact with drugs - G-protein coupled receptors (GPCR) interact with drugs through 7 regions of proteins that span and innervate the cell membrane and trap the molecule into the receptor site like an interwoven basket (Insel & Sriram, 2018). Drugs can then enter this space and interact with the GRCP. A specific interaction and binding with a site on one or more of the regions of proteins within the GPCR, and drugs bound with the GRCP can stimulate t...

NR546 Midterm Exam 2023/2024 Questions And Answers Update A+. What should the PMHNP consider when prescribing chemical restraints? - Answer-- allergy status -prior med hx for adverse drug reactions r/t the meds ordered in the chemical restraint -state regulations regarding chemical restrains must be reviewed Are the PMHNP and other staff liable if the client has an allergic reaction or adverse side effects to the drugs used for chemical restraint? - Answer-No. The client has been court-or...

CPJE Top Drugs & Doses Exam With 100% Correct Answers 2024 flexeril - answercyclobenzaprine muscle relaxant 5 - 10mg TID prn xerostomia, serotonergic, careful heart dx lioresal - answerbaclofen muscle relaxant 5-20mg tid - qid prn avoid abrupt withdrawal robaxin - answermethocarbamol muscle relaxant 1.5g - 2g qid prn hypotension (bp) skelaxin - answermetaxalone muscle relax 800mg tid - qid prn hepatox, somnolence soma C4 - answercarisoprodol CIV muscle relax 250 - 350mg qid ...

Prodrug - Answer An inactive drug dosage form that is converted to an active metabolite by various biochemical reactions once it is inside the body. -Cytochrome P450 -Ex. Aspirin, psilocybin, heroin Bioavailability - Answer the rate at and the extent to which a nutrient is absorbed and used -Affected by route of administration and drug dosage -Drug clearance (rate drug leaves circulation) -Steady state concentration -Affected by chemical stability, solubility, and first pass Steady stat...

Chapter 1. An Introduction to Pharmacogenetics Multiple Choice Identify the choice that best completes the statement or answers the question. 1. Genetic polymorphisms account for differences in metabolism, including: 1. Poor metabolizers, who lack a working enzyme 2. Intermediate metabolizers, who have one working, wild-type allele and one mutant 3. Extensive metabolizers, with two normally functioning alleles 4. All of the above 2. Up to 21% of Asians are ultra-rapid 2D6 metabolizer...

NR546 Midterm Exam 2023/2024 Questions And Answers Update A+. What should the PMHNP consider when prescribing chemical restraints? - Answer-- allergy status -prior med hx for adverse drug reactions r/t the meds ordered in the chemical restraint -state regulations regarding chemical restrains must be reviewed Are the PMHNP and other staff liable if the client has an allergic reaction or adverse side effects to the drugs used for chemical restraint? - Answer-No. The client has been court-or...