Nigrostriatal pathway Study guides, Class notes & Summaries

NURS 660 Exam1 LATEST UPDATE 2023 QUESTIONS AND EXPLAINED ANSWERS|AGRADE 1. Identify the emerging neurobiological hypothesis of schizophrenia. o The hypothesis: (focus on the most detail with the Dopamine Theory) The only pharmacological treatment that we have are dopamine (D2 receptors) and serotonin (5HT2A) Dopamine Theory ▪ Hyperactive dopamine at D2 receptors in the mesolimbic pathway In the mesolimbic pathway is responsible for the positive symptoms; the hypoactivity is res...

NURS 4010 Unit 1 Exam Antipsychotic/Neuroleptic Medications Questions With Verified Answers Bind with dopamine receptors (commonly D2 receptors - in all 4 pathways of the brain, causing side effects) MOA of Antipsychotic/Neuroleptic Medications Antipsychotics Used for schizophrenia, paranoia, psychosis, mania, severe anxiety, Tourette's, autism; Note: just b/c someone is on an antipsychotic does not mean they have a thought disorder; Metabolized by the liver and excreted in urine, feces...

Summary NSG 552 Psychopharmacology Exam 1 Study Guide LATEST 2024. DOPAMINE • Dopamine belongs to the family of catecholamines. It is a neurotransmitter. • Hormones, Epinephrine and Norepinephrine (other catecholamines) are derived from Dopamine • Dopamine plays a significant role in learning, goal-directed behavior, regulation of hormones, motor control. DOPAMINE SYNTHESIS Phenylalanine (amino acid from diet) -> phenyalanine hydroxylase -> Tyrosine -> Tyrosine hydroxylase ...

Drug name Indication Target symptoms: state if positive or negative effect Potency (if noted. receptor occupancy if noted ) Neurotransmitter(s) affected Half-life (T1/2), metabolism (CYP 450 enzyme) Notable side effects (associate to pathway or NT) Typical antipsychotics (conventional) Haloperidol Treats positive symptoms Prescribed for manifestations of psychotic disorders, Tics and vocal utterances in Tourette’s syndrome Blocks dopamine 2 receptors, reducing positive symptoms ...

Drug name Indication Target symptoms: state if positive or negative effect Potency (if noted. receptor occupancy if noted ) Neurotransmitter(s) affected Half-life (T1/2), metabolism (CYP 450 enzyme) Notable side effects (associate to pathway or NT) Typical antipsychotics (conventional) Haloperidol Dopamine Receptor Antagonist Targets the symptoms of psychosis such as hallucinations and delusions. It can also be used to treat the tics and vocalizations of Tourette’s, as a second-l...

ANCC PMHNP Exam Prep Questions and Answers (2024) (Verified Answers) mesocortical pathway executive function: attention, focus, depression nigrostriatal pathway from substantia nigra (brainstem) to striatum (muscles): Parkinson's mesolimbic pathway projects to nucleus accumbens (part of limbic system). Pleasure, reward, positive symptoms of schizophrenia: Addiction, gambling Tuberoinfundibular pathway regulation of prolactin (acts on pituitary). Hypersexuality in mania ...

NSG 552 Psychopharmacology Exam 1 Study Guide Complete Updated 2024/2025. Phenylalanine (amino acid from diet) -> phenyalanine hydroxylase -> Tyrosine -> Tyrosine hydroxylase -> DOPA -> Dopa decarboxylase -> Dopamine KEY POINT: Dopamine is synthesized directly from tyrosine or indirectly from phenylalanine • Dopamine is packed and stored into synaptic vesicles via the vesicular monoamine transporter (VMAT2) and stored until its release into the synapse. • When dopamine...

How does the orbitofrontal cortex (OFC) affect the amygdala? - CORRECT ANSWER inhibits and activates the amygdala Wernicke's area is associated with which of the following? - CORRECT ANSWER speech comprehension The limbic system is associated with which of the following - CORRECT ANSWER emotion and learning Which brain structure is most associated with long term memory? - CORRECT ANSWER hippocampus When prescribing psychotropic medications, the PMHNP knows that t...

NURS 4010 Unit 1 Exam Antipsychotic/Neuroleptic Medications Questions With Verified Answers Bind with dopamine receptors (commonly D2 receptors - in all 4 pathways of the brain, causing side effects) MOA of Antipsychotic/Neuroleptic Medications Antipsychotics Used for schizophrenia, paranoia, psychosis, mania, severe anxiety, Tourette's, autism; Note: just b/c someone is on an antipsychotic does not mean they have a thought disorder; Metabolized by the liver and excreted in urine, feces...

mesocortical pathway - ANSWER executive function: attention, focus, depression nigrostriatal pathway - ANSWER from substantia nigra (brainstem) to striatum (muscles): Parkinson's mesolimbic pathway - ANSWER projects to nucleus accumbens (part of limbic system). Pleasure, reward, positive symptoms of schizophrenia: Addiction, gambling Tuberoinfundibular pathway - ANSWER regulation of prolactin (acts on pituitary). Hypersexuality in mania Dopamine - ANSWER produced in substania nigra ...