Mesolimbic pathway Study guides, Class notes & Summaries
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Exam (elaborations) NURS 660
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dopamine hypothesis - ANSWER the theory that schizophrenia results from excessive 
activity of the neurotransmitter dopamine 
What is the path of dopamine suppression by 5-HT? - ANSWER 5-HT2A antagonism 
by atypical antipsychotics decrease serotonin release, thereby stimulating downstream 
dopamine. Increased dopamine reduces glutamate which inhibits release of inhibitory 
GABA (inhibits dopamine) 
Mesolimbic dopamine hypothesis: Hyperactivity of dopamine neurons in the mesolimbic 
dopamine...
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NURS 660 Exam1 LATEST UPDATE 2023 QUESTIONS AND EXPLAINED ANSWERS|AGRADE
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NURS 660 Exam1 LATEST UPDATE 2023 
QUESTIONS AND EXPLAINED 
ANSWERS|AGRADE 
1. Identify the emerging neurobiological hypothesis of schizophrenia. 
o The hypothesis: (focus on the most detail with the Dopamine Theory) 
 The only pharmacological treatment that we have are dopamine (D2 
receptors) and serotonin (5HT2A) 
 Dopamine Theory 
▪ Hyperactive dopamine at D2 receptors in the mesolimbic 
pathway 
In the mesolimbic pathway is responsible for the positive 
symptoms; the hypoactivity is res...
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Exam 4: NURS660/ NURS 660 (NEW 2023/ 2024) Psychopharmacology and Advanced Mental Health Exam |Grade A | Questions and Verified Answers - Maryville
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Exam 4: NURS660/ NURS 660 (NEW 2023/ 
2024) Psychopharmacology and Advanced 
Mental Health Exam |Grade A | Questions 
and Verified Answers - Maryville 
Question 
 Why do some people with ADHD abuse cocaine? What MOA does cocaine affect the same as 
methylphenidate? 
 
 
Answer: 
they have the same key binding site for the serotonin 2a receptor 
 
 
 
Question 
 MOA of naltrexone how does it help people come OFF alcohol? 
 
 
Answer: 
by blocking mu receptors to induce euphoria 
 
 
 
Quest...
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Final Exam: NR546/ NR 546 (Latest 2024/ 2025 Update) Psychopharmacology for the PMHNP Review -Questions and Verified Answers -100% Correct-Grade A-Chamberlain
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Final Exam: NR546/ NR 546 (Latest 2024/ 2025 Update) Psychopharmacology for the PMHNP Review -Questions and Verified Answers -100% Correct-Grade A-Chamberlain 
 
Q: Hallucinogenic intoxication 
 
 
Answer: 
 pupillary dilation, tachycardia, sweating, palpitations, blurred vision, tremors, incoordination 
Can be perceived as a panic attack and often called a bad trip. 
Can experience an acute state of confusion (delirium) where the abuser is disoriented and agitated. 
 
 
 
Q: Disulfiram 
 
 
An...
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ANCC PMHNP Exam Prep Question with complete solution 2023
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ANCC PMHNP Exam Prep Question with complete solution 2023mesocortical pathway 
executive function: attention, focus, depression 
 
 
 
nigrostriatal pathway 
from substantia nigra (brainstem) to striatum (muscles): Parkinson's 
 
 
 
mesolimbic pathway 
projects to nucleus accumbens (part of limbic system). Pleasure, reward, positive symptoms of schizophrenia: Addiction, gambling 
 
 
 
Tuberoinfundibular pathway 
regulation of prolactin (acts on pituitary). Hypersexuality in mania 
 
 
 
Dopam...
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NR 546 / NR546 Actual Final Exam 2024/2025 Prediction 70 Questions (All Correct Answers, Already Graded A)
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Which of the following is considered the pleasure center of the brain? 
A. Cortico-striatal-thalamic-cortical loop 
B. Mesolimbic dopamine pathway 
C. Mesocortical dopamine pathway 
D. None of the above - B. Mesolimbic dopamine pathway 
The reactive reward system signals the immediate prospect of pleasure or pain and triggers drug-seeking behavior. 
A. True 
B. False - A. True 
What role does the amygdala play in substance abuse? 
A. Releases phasic bursts of dopamine to the nucleus accumbens wh...
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Psychopharm Stahl Final Exam Questions and Correct Answers
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Which of the following is considered the pleasure center of the brain? 
A. Cortico-striatal-thalamic-cortical loop 
B. Mesolimbic dopamine pathway 
C. Mesocortical dopamine pathway 
D. None of the above - B. Mesolimbic dopamine pathway 
The reactive reward system signals the immediate prospect of pleasure or pain and triggers drug-seeking behavior. 
A. True 
B. False - A. True 
What role does the amygdala play in substance abuse? 
A. Releases phasic bursts of dopamine to the nucleus accumbens wh...
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NR 546 Week 3: NR 546 Week 3 Study Guide: Updated Solution
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Indication 
Target symptoms: state if positive or negative effect Potency (if noted. receptor occupancy if noted ) Neurotransmitter(s) affected	Half-life (T1/2), metabolism (CYP 450 
enzyme)	Notable side effects (associate to pathway or NT) 
Typical antipsychotics (conventional) 
Blocks dopamine 2 receptors, reducing positive symptoms of psychosis and possibly combative, explosive, and hyperactive behaviors Blocks dopamine 2 receptors in the nigrostriatal pathway, improving tics and other sympto...
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LMR - Georgette's flashcard 2023/2024
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LMR - Georgette's flashcard 2023/2024 
 
 
LMR - Georgette's flashcard 2023/2024 
Terms in this set (526) 
 
 
What drugs should be avoided with Kava Kava?	 
Alprazolam 
CNS depressants (e.g., phenobarbital, zolpidem) 
 
What is the normal range for TSH?	 
0.5 - 5.0 mu/L 
 
What are lab values in Hyperthyroidism	 
Decreased TSH Increased T4 and T3 
 
What are labs in Hypothyroidism?	 
Increased TSH Decreased T4 and T3 
	 
Heat intolerance 
What are 5 primary symptoms of	Agitation, Anxiety, Irr...
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NR 546 / NR546 Actual Final Exam 2024 / 2025 Prediction Questions (All Correct Answers, Already Graded A)
- Exam (elaborations) • 28 pages • 2024
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Available in package deal
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- $12.00
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Which of the following is considered the pleasure center of the brain? 
A. Cortico-striatal-thalamic-cortical loop 
B. Mesolimbic dopamine pathway 
C. Mesocortical dopamine pathway 
D. None of the above - B. Mesolimbic dopamine pathway 
The reactive reward system signals the immediate prospect of pleasure or pain and triggers drug-seeking behavior. 
A. True 
B. False - A. True 
What role does the amygdala play in substance abuse? 
A. Releases phasic bursts of dopamine to the nucleus accumbens wh...
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