Ester local anesthetics - Study guides, Class notes & Summaries

Liver What is the primary location of biotransformation or metabolism of amide-type local anesthetics. Blood Plasma What is the primary location of biotransformation or metabolism of ester-type local anesthetics. Previous Play Next Rewind 10 seconds Move forward 10 seconds Unmute 0:01 / 0:15 Full screen Brainpower Read More Vasodilators What is the action of all local anesthetic drugs in dentistry. Resting Plasma Epinephrine What is the level of ephinephrin...

general anesthesia causes loss of sensation, consciousness, and reflexes injectable or inhalation local anesthesia causes loss of sensation without loss of consciousness (specific body area) Anesthesia Assessment risk factors: older adult more susceptible, airway patency, titrate carefully General anesthesia assessment family history of malignant hyperthermia resp. disease (hypoventilation) cardiac disease (dysrhythmias, altered cardiac output) gastric contents (aspiration) alcohol...

1) GENERAL PRINCIPLES OF PHARMACOLOGY PART I PHARMACOKINETICS 001. Pharmacokinetics is: a) The study of biological and therapeutic effects of drugs b) The study of absorption, distribution, metabolism and excretion of drugs c) The study of mechanisms of drug action d) The study of methods of new drug development 002. What does “pharmacokinetics” include? a) Complications of drug therapy b) Drug biotransformation in the organism c) Influence of drugs on metabolism proce...

Pharmacologic behavior (AAPD QE Prep Dr. Nelson) Exam Questions With Verified Answers What was the chronology of anesthetic discovery (starting with cocaine till now)? - answer1) Cocaine (1885) 2) Procaine (1904) 3) Lidocaine (1943) 4) Articaine (2000) What Cranial nerve do we block most frequently in dentistry? what are its branches and functions? - answer1) Cranial Nerve (V); Trigeminal Nerve 2) 3 Branches: a) V1: Opthalmic branch b) V2: Maxillary branch (Superior alveolar, etc) c...

Pharmacologic behavior (AAPD QE Prep Dr. Nelson) Exam Questions With Verified Answers What was the chronology of anesthetic discovery (starting with cocaine till now)? - answer1) Cocaine (1885) 2) Procaine (1904) 3) Lidocaine (1943) 4) Articaine (2000) What Cranial nerve do we block most frequently in dentistry? what are its branches and functions? - answer1) Cranial Nerve (V); Trigeminal Nerve 2) 3 Branches: a) V1: Opthalmic branch b) V2: Maxillary branch (Superior alveolar, etc) c...

Nitroglycerin MOA - converts nitric oxide to active form, which causes DILATION of arterial and venous vessels, decreasing myocardial oxygen demand Venous dilation causes... - decreased preload and peripheral vascular resistance Arterial dilation causes... - reduced systemic vascular resistance and pressure, which causes decreased afterload Nitroglycerin pharmacokinetics - - lipid-soluble --> easily crosses membranes - FIRST-PASS EFFECT, so not usually given PO **important to educate p...

what are anesthetics correct answers drugs that cause complete or partial loss of senation general anesthetics are... correct answers CNS depressants use to produce loss of pain sensation consciousness local anesthetics are... correct answers drugs used to cause loss of pain sensation and feeling in a designated area of the body without systemic effects associated with severe CNS depression amnesia correct answers loss of memory of an event or procedure analgesia correct answers loss...

Anesthesia Clerkship Exam 2023 Signs of mast cell degranulation and/or a histamine mediated reaction (signs of a true allergic rxn) - ANS-Hypotension, hives, bronchospasm, flushing, rash Signs of elevated serum levels of local anesthetic - ANS-Dizziness, seizures, dysrhythmias, tinnitus If a true local anesthetic allergy does exist, it is most likely to an _____ based local anesthetic rather than an ____ based one. - ANS-ester; amide Continue or d/c on day of surgery: H2 blockers - ANS...

esthetic (structure/composition-wise) and there roles. - answer1) Lipophilic (to penetrate anatomic barrier) 2) Intermediate chain (amide or ester, distinguishes area of metabolism) 3) Hydrophilic (ensures that drug will not precipitate in interstitial fluid/space) T or F: Local anesthetics are weak acids with a pKa of 7.5-9.5) - answerFALSE, LA are weak BASES with a pKa of 7.5-9.5) what determines the Non-Ionized (basic) % of anesthetic? - answer1) Tissue pH determines % of un-ionized LA...

Focus on Nursing Pharmacology - Amy M. Karch - Chapter 27 Exam with Complete Solutions 100% Solved amnesia - answerloss of memory of an event or procedure Analgesia - answerloss of sensibility to pain anesthesia - answerrefers not only to loss of pain but to loss of all other sensations balanced anesthesia - answeruse of combinations of drugs to accomplish what inhalation anesthetic can not do alone general anesthetics - answerproduce unconsciousness and lock of response to all painful ...