Drug discovery - Study guides, Class notes & Summaries

Innate immune system - ANSWER-nonspecific defense mechanisms that come into play immediately or within hours of an antigen's appearance in the body -antigens are foreign substances such as toxins, bacteria, viruses -the defense mechanisms involve physical barriers such as skin, chemicals in blood, and immune system cells that attack foreign cells in body the chemical or molecular properties of the antigen - ANSWER-what is the innate immune response activated by? acquired immune system -...

Drug Discovery Final Exam | with complete solution | Latest 2024/25

Pharmacology /INTRODUCTION TO DRUG DISCOVERY TEST 100% VERIFIED SOLUTIONS 2023/2024 Who used Quinine and what for? • South American Indians: treat chills and fever • Europeans: Treat fever and malaria What is quinine used for? treat malaria What was opium poppy initially used for? Analgesic effects What drugs are found in opium poppy • Morphine (analgesic agent) • Codeine (cough suppressant) Erythroxylum coca contains coca Erythroxylum coca is used for • Stimul...

Pharmacology 1 Exam 1- PA First Semester Pharmacology Drug Development Process Phases Drug Discovery Pre-Clinical Clinical Trials (phases 1, 2, 3) FDA Review Production What happens between Clinical Trials and FDA Review? NDA is sent to the FDA How much does it cost to produce a new drug? $1-2 billion dollars When does the

OPENSTAX MICROBIOLOGY TEST BANK OpenStax Microbiology THIS TEST BANK COVERS ALL CHAPTERS 1-26 OF THE BOOK 1 An Invisible World 1.1 What Our Ancestors Knew 1.2 A Systematic Approach 1.3 Types of Microorganisms 2 How We See the Invisible World 2.1 The Properties of Light 2.2 Peering Into the Invisible World 2.3 Instruments of Microscopy 2.4 Staining Microscopic Specimens 3 The Cell 3.1 Spontaneous Generation 3.2 Foundations of Modern Cell Theory 3.3 Unique Characteristics of Prokaryotic Cells 3.4 ...

Lipinski's Rule of 5 - ANSWER-A successful drug meets these criteria: -LogP<5 -molecular weight <500 g/mol - hydrogen bond donors <5 -hydrogen bond acceptors <10 -rotatable bonds<10 logD - ANSWER-distribution between all forms of drug (logD<5) Polar surface area - ANSWER-the surface area of nitrogen's, oxygens, and their attached protons on a molecule What is the problem with Lipinski's rules - ANSWER-the majority of drugs that are being focused on only adhere ...

OPENSTAX MICROBIOLOGY TEST BANK OpenStax Microbiology THIS TEST BANK COVERS ALL CHAPTERS 1-26 OF THE BOOK 1 An Invisible World 1.1 What Our Ancestors Knew 1.2 A Systematic Approach 1.3 Types of Microorganisms 2 How We See the Invisible World 2.1 The Properties of Light 2.2 Peering Into the Invisible World 2.3 Instruments of Microscopy 2.4 Staining Microscopic Specimens 3 The Cell 3.1 Spontaneous Generation 3.2 Foundations of Modern Cell Theory 3.3 Unique Characteristics of Prokaryotic Cells 3.4 ...

Texas Jurisprudence Exam questions and answers latest top score. Can a patient successfully sue a doctor if there is no physician-patient relationship? - correct answers.No If there is no prior physician-patient relationship, are you legally obliged to respond to a call from a patient for treatment? - correct answers.No Does being on call give rise to a physician-patient relationship? - correct answers.No How can one terminate a physician-patient relationship,...

TEST BANK Pharmacology Clear and Simple: A Guide to Drug Classifications and Dosage Calculations Cynthia J. Watkins 4th Edition Chapter 1. History of Pharmacology MULTIPLE CHOICE 1. The Greek word pharmakon means which of the following? a. Medicine b. Poison c. Remedy d. Medicine, poison, and remedy ANS: D Rationale: The word pharmakon refers to the curing of illness, thus meaning medicine and remedy, as well as poison because early medicines we...

1. How are drugs sorted into therapeutic groups and classes? A. first by the conditions that they are used to treat. and then by their mechanisms of action B. first by their mechanisms of action. and then by their therapeutic effects C. first by their side effects. and then by their therapeutic effects D. first by their toxicity. and then by their effectiveness 2. Bone marrow transplants... A. require that the patient first undergo chemotherapy or radiation to kill the diseased...