Cytochrome p450 - Study guides, Class notes & Summaries

Midterm Exam: NR565 / NR 565 (Latest Update 2024 / 2025) Advanced Pharmacology Fundamentals | Review Study Guide | 100% Correct | Grade A - Chamberlain Question: Beer's Criteria Answer: Includes five lists that describe certain medications and situations that include potentially inappropriate medication (PIM) use in older adults. PIM d/t medication-disease or medication-syndrome to be used cautiously in older adults Medications to be avoided or dosage, decreased in the presence ...

Most cytochrome P450 enzymes alter the activity of drugs by: correct answers Cytochrome P450 acts as monooxygenases, where an oxygen atom is inserted into a substrate (the drug of interest), thereby resulting in the oxidation of the substrate. During phosphorylation of STAT5b proteins,phosphate groups are exchanged for what atoms on tyrosine residues? correct answers The passage notes that JAK2 is a tyrosine kinase. Tyrosine has a nucleophilic hydroxyl group that attacks the terminal phosphat...

During what trimester is a pregnant woman most at risk for adverse drug reactions with potential long term consequences? 1st trimester (fetus most at risk d/t rapid growth) What is BEERS criteria? Recommendations of medications inappropriate for elderly (65 and older), prescriber ultimately decides What is the CYP450 (cytochrome P450) liver enzyme system where medications are metabolized, can either be inducers or inhibitors and create drug-drug interactions CYP450 inducers Speed up metabo...

NR565 ADVANCED PHARMACOLOGY FUNDAMENTALS EXAM REVIEW QUESTIONS AND ANSWERS, GRADED A+ Pharmacokinetics - -The process by which drugs are absorbed, distributed within the body, metabolized, and excreted. Pharmacodynamics - -The study of what the drug does to the body Factors Affecting Drug Absorption - -Rate of dissolution Surface area Blood flow Lipid solubility pH partitioning Factors Affecting Drug Distribution - -Blood flow to tissues Ability to exit the vascular system Blood-bra...

Midterm Exam: NR546/ NR 546 Psychopharmacology for the Psychiatric-Mental Health Nurse Practitioner MIDTERM Exam Review | Complete Guide Questions and Verified Answers| 2023/ 2024 Updated!! – Chamberlain What should the PMHNP consider when prescribing chemical restraints? - ANSWER -allergy status -prior med hx for adverse drug reactions r/t the meds ordered in the chemical restraint -state regulations regarding chemical restrains must be reviewed Are...

NRNP 6566 WK1-5 Midterm Questions and Answers 100% Pass **What is the Cytochrome P450 system responsible for?** A) Breaking down carbohydrates B) Metabolizing medications C) Synthesizing proteins D) Producing energy ** Answer: B) Metabolizing medications** **What do inhibitors of the Cytochrome P450 system do?** A) Enhance metabolic activity B) Have no effect on enzyme function C) Block metabolic activity from one or more CYP450 enzymes D) Reduce enzyme synthesis ** Answer...

NR 546 Midterm Exam 2023/2024 Questions AND Answers Update A+ What should the PMHNP consider when prescribing chemical restraints? - Answer-- allergy status -prior med hx for adverse drug reactions r/t the meds ordered in the chemical restraint -state regulations regarding chemical restrains must be reviewed Are the PMHNP and other staff liable if the client has an allergic reaction or adverse side effects to the drugs used for chemical restraint? - Answer-No. The client has been court-...

First Pass Metabolism - Answer GI Tract ---> Portal Circulation ---> Liver --->Metabolized ---> Systemic Circulation 1st pass metabolism lowers the amount of drug available. If high first-pass effect, mostly becomes inactivated and cannot be used, these meds cannot be given orally. Example: Insulin Drug Metabolism - Answer The most active organ is the LIVER (Cytochrome P450 enzyme system) Others are Kidneys, GI Tract, Lungs Coumadin and Bactrim - Answer Sulfa dru...

Advanced Pharmacology- FNP Exam Questions with Correct Answers 100% Verified 2024/2025 True or False: Children metabolize drugs faster than adults. - Correct Answer True which are easier to excrete: water soluble drugs or lipid soluble drugs? - Correct Answer Water soluble What are the cytochrome p450 inducers? (CRAPGPS) - Correct Answer Carbamazapine Rifampin Alcohol Phenytoin Griseofulvin Phenobarbital Sulfonylureas and St. Johns Wort what do CYP450 inducers do? - Correct An...

Test Bank for Davis's Drug Guide for Nurses, 19e 19th Edition by April Hazard Vallerand, Cynthia A. Sanoski. Complete guide with Next Gen NCLEX Type questions included. How To Use Davis’s Drug Guide For Nurses Evidence-Based Practice And Pharmacotherapeutics: Implications For Nurses Pharmacogenomics Medication Errors: Improving Practices And Patient Safety Detecting And Managing Adverse Drug Reactions Overview Of Risk Evaluation And Mitigation Systems (Rems) Special Dosing Considerat...