Tufts pharmacology exam - Study guides, Class notes & Summaries

According to textbooks, local anesthetics fall into the following classes in terms of duration of action... wha tis short? - ANSWER Procaine What is moderate? - ANSWER Prilocaine, mepivicaine, lidocaine What is long? - ANSWER Bupivacaine, tetracaine, etidocaine How does propranolol interact with lidocaine? - ANSWER 1. By slowing down the heart via beta receptor blockade, blood delivery (and lidocaine) to the liver is reduced, thus lidocaine remains in the systemic circulation longer and ca...

which of the following is contraindicated in a patient who had an allergic reaction to procaine six months ago? a. nerve block with lidocaine b. topical application of lidocaine c. topical application of tetracaine d. infiltration with an antihistamine - ANSWER c

Hypotensive shock may result from excessive blood levels of each of the following local anesthetics EXCEPT a. Cocaine b. Procaine c. Lidocaine d. Tetracaine e. Mepivacaine e. Preventing an increase in membrane permeability to Na+

What happens w/Penicillin AND tetracycline? - ANSWER Cancel each other out What does Probenecid do? - ANSWER Prolongs penicillin by altering renal clearance. Uric acid reducer Broad spectrum antibiotics do what to Coumadin? - ANSWER Enhance it. (bind up vitamin k)

High plasma levels of LA can effect the CNS how? - ANSWER Initially CNS stimulation following CNS depression How do high plasma levels of LA cause CNS depression? - ANSWER Inhibition of inhibitory and excitatory neurons at higher doses What is the first sign your patient may experiencing toxicity from too much epi? - ANSWER Elevated pulse rate

What are symptoms seen during allergic reactions to penicillins? - ANSWER 1. Dermatitis 2. Stomatitis 3. Bronchoconstriction 4. Cardovascular collapse What agent produces GI upsets and pseudomonas colitis? - ANSWER Clindamycin Which agents are most likely to cause superinfection? - ANSWER Broad spectrum agents