Tufts pharmacology - Study guides, Class notes & Summaries

Tufts Pharmacology;NBDE II Review Exam 2023 Questions and Answers with complete solution

List 3 esters - ANSWER Procaine Tetracaine Cocaine Where are amides metabolized? - ANSWER Liver Where are esters metabolized? - ANSWER Pseudocholinesterases in plasma What drug group has the most consistent drug structure? - ANSWER LA What LA causes methemoglobinemia? - ANSWER Prilocaine

Prazosin - ANSWER-HTN, alpha1 blocker, inhibits release of norepinephrine Methyldopa - ANSWER-HTN, acts centrally to stimulate alpha receptors Clonidine - ANSWER-HTN, stimulates alpha2 receptors in CNS Propranolol - ANSWER-HTN, nonselective beta blocker Metoprolol - ANSWER-HTN, selective beta1 blocker Hydralazine - ANSWER-HTN, directly acts to vasodilate vascular smooth muscle Chlorothiazide - ANSWER-HTN, diuretic, thiazide, when administered with digitalis, will increase penet...

which of the following is contraindicated in a patient who had an allergic reaction to procaine six months ago? a. nerve block with lidocaine b. topical application of lidocaine c. topical application of tetracaine d. infiltration with an antihistamine - ANSWER c

Hypotensive shock may result from excessive blood levels of each of the following local anesthetics EXCEPT a. Cocaine b. Procaine c. Lidocaine d. Tetracaine e. Mepivacaine e. Preventing an increase in membrane permeability to Na+

What are symptoms seen during allergic reactions to penicillins? - ANSWER 1. Dermatitis 2. Stomatitis 3. Bronchoconstriction 4. Cardovascular collapse What agent produces GI upsets and pseudomonas colitis? - ANSWER Clindamycin Which agents are most likely to cause superinfection? - ANSWER Broad spectrum agents

What happens w/Penicillin AND tetracycline? - ANSWER Cancel each other out What does Probenecid do? - ANSWER Prolongs penicillin by altering renal clearance. Uric acid reducer Broad spectrum antibiotics do what to Coumadin? - ANSWER Enhance it. (bind up vitamin k)