The lac repressor is - Study guides, Class notes & Summaries

All cells that make up an organism contain the exact same DNA sequence (genome) however individual cell-types look and function very differently. Why? Correct Answer-each cell-type expresses a unique set of genes of the genomic DNA. Speaking of genotype and phenotype how are these terms defined? Correct Answer-the genotype defines the genetic information (gene) and the phenotype the outcome of gene expression. Which of the following describes a functional gene? Correct Answer-a gene is def...

Core Promoter Elements ~~> TATA box = repetitive sequence of thymine and adenine Initiator (INR) = sequence of pyramidines like thymine and cytosine DPE = downstream promoter elements found along the DNA Common to have >1 promoter but not all of them CpG islands ~~> Sequences high in CG frequency. They are able to escape methylation which would lead to gene silencing. Demethylation would lead to over expression of genes. Regulatory Promoter Elements ~~> UAS and URS f...

iology 1000 – Principles of Biology ( BioS 115 Core II: Genetics) Exam Study Guide. Explain the concepts of penetrance and expressivity Penetrance is the percentage of cases in which a certain phenotype is expressed. There are two types: i. Complete Penetrance: when 100% is correlated to the genotype. So, all express the same thing. ii. Incomplete: this is when some are identical, and others are different. Penetrance= # with genotype showing phenotype x 100 # with the genotype Expressi...

Biology 1000 – Principles of Biology ( BioS 115 Core II: Genetics) Exam Study Guide 2024/2025. Review discussion about Breast Cancer Breast Cancer (BRCA1 and BRCA2) c. Provides instructions for making a protein that acts as a tumor suppressor d. Prevents cells from growing and dividing e. Accounts for 30-40% of families with breast cancer cases Penetrance and BRCA a. Refers to the risk of developing breast and ovarian cancer b. A reliable estimate of penetrance is crucial for medical co...

19.1 Discuss why beneficial mutations are rare & suggest a process that beneficial mutations underpin (4 MARKS) - ️️Majority of mutations are silent (1); idea that random change to protein structure is more likely to reduce function (1); idea that beneficial mutations increase chances of survival if environment changes (1); surviving organisms reproduce and pass new alleles to offspring (1); leading to evolution (1) 19.1 Outline why majority of mutations do not have an influence phenotype (...

QBM Exam Questions And Answers With Complete Solutions 2024 What are the first three steps for starting a project? - answer1 ) Choose 2) Read literature 3) Obtain DNA sequence Once you obtain the DNA sequence in the beginning of a project, BLAST will allow what? - answer"Basic Local Alignment Search Tool" - To search for homology (duplication events) - Can predict protein, molecular weight, pI, and extinction coefficient - Predict the secondary/tertiary structure, transmembrane helice...

What will be the effect on transcription when an inhibitor is in play? A. Allow transcription B. Prevent transcription - Answer-B Explanation: An inhibitor prevents activator from binding to DNA; activators are used in positive regulation (increasing transcription) - thus, the inhibitor prevents the activator from positive regulating (increasing) transcription. What will be the effect on transcription when an inducer is in play? A. Allow transcription B. Prevent transcription - Answer-A Ex...

What will be the effect on transcription when an inhibitor is in play? A. Allow transcription B. Prevent transcription - Answer-B Explanation: An inhibitor prevents activator from binding to DNA; activators are used in positive regulation (increasing transcription) - thus, the inhibitor prevents the activator from positive regulating (increasing) transcription. What will be the effect on transcription when an inducer is in play? A. Allow transcription B. Prevent transcription - Answer-A Ex...

Explain the concepts of penetrance and expressivity Penetrance is the percentage of cases in which a certain phenotype is expressed. There are two types: i. Complete Penetrance: when 100% is correlated to the genotype. So, all express the same thing. ii. Incomplete: this is when some are identical, and others are different. Penetrance= # with genotype showing phenotype x 100 # with the genotype Expressivity is the type or degree to which a penetrant gene ( the genes carrying the mutatio...

QBM Exam Questions And Answers With Complete Solutions 2024 What are the first three steps for starting a project? - answer1 ) Choose 2) Read literature 3) Obtain DNA sequence Once you obtain the DNA sequence in the beginning of a project, BLAST will allow what? - answer"Basic Local Alignment Search Tool" - To search for homology (duplication events) - Can predict protein, molecular weight, pI, and extinction coefficient - Predict the secondary/tertiary structure, transmembrane helice...