Pcol 824 Study guides, Class notes & Summaries

PCOL 824 Final Exam | with complete solution | Latest 2024/25

PCOL 824 Exam 3 Questions with Correct Answers cholinergic receptor sites are either.... - Answer-muscarinic or nicotinic cardiac muscle - Answer-M-2 (cholinergic) exocrine glands - Answer-M-3 (cholinergic) smooth muscle - Answer-M-3 (cholinergic) ganglia (PNS & SNS) & adrenal medulla - Answer-N-neuronal (cholinergic) skeletal muscle end plate - Answer-N-muscle (cholinergic) sweat glands (sympathetic NS) - Answer-M-3 (cholinergic) brain & spinal cord - Answer-M-1, N...

PCOL 824 DRUGS Exam Questions and Answers All Correct ACE inhibitors suffix - Answer--pril ACE inhibitor that has a Short Half Life - Answer-Captopril ACE inhibitors MOA - Answer-Inhibit ACE--> decrease angiotensin II--> decrease GFR (prevent constriction of efferent arteriole) Increasing levels of renin (loss of feedback) ACE inhibition--> prevents inactivation of bradykinin (vasodilator) Bradykinn increase, Cough ACE-2 does it degrade angiotensin II - Answer-ACE-2 de...

PCOL 824 Final Exam Questions with Answers All Correct serotonin receptor (5HT2C) - Answer-serotonin binding activates the satiety pathway leptin - Answer--hormone produced in fat cells -stimulates the satiety pathway and inhibits the hunger pathway ghrelin - Answer-stimulates the NPY pathway (hunger) amphetamine-like drugs - Answer--short term management of obesity (appetite suppressant) ADR: weight rebound orlistat - Answer-irreversible inhibitor of GI lipase (decreases fat a...

PCOL 824 Test 2 Questions with Correct Answers Types of bonds often seen in Drug-ReceptorInteractions - Answer-Electrostatic Interactions: (strongest first) 1) Salt Bridges (ion-ion) (full charge on full charge Na+Cl-, much stronger) 2) Pi-Cation (ion-dipole) the ion-dipole interaction (i.e. a fully charged species interacting with the opposite charge of a dipole) 3) Neutral H-Bonds (dipole-dipole) 4) Van der waals (C to C) *Aliphatic chains to Aliphatic chains Aliphatic chains to ar...

PCOL 824 Exam 2 Questions with Correct Answers What is the equation for Vd? - Answer-Vd = initial dose of drug in body / concentration of drug in plasma High Vd - Answer-Drug is mostly found in tissues - not affected by changes to protein binding - favored being present in the cells Low Vd - Answer-Drug is mostly in blood - very protein bound (albumin) - sensitive to changes in protein binding Order of Lowest to Highest Vd - Answer-Drug that highly binds to proteins and cannot enter t...

PCOL 824 Exam 1 2024 Questions with 100% Correct Answers Verified A+

list the choline esters (muscarinic agonists) - - acetylcholine - methacholine - carbachol - bethanechol what are the indications for muscarinic agonists? - - post operative urinary retention - decrease intraocular pressure - cause miosis during cataract removal - xerostomia in cancer patients what is cevimeline? - - muscarinic agonist - activates M3 for dry mouth list the reversible anticholinesterase agents and their function - - physostigmine = peripheral CNS effects - neostigmin...